Self-terminating AF depends on electrical remodeling while persistent AF depends on additional structural changes in a rapid atrially paced sheep model

W Anné, R Willems, P Holemans, F Beckers… - Journal of molecular and …, 2007 - Elsevier
The development of atrial fibrillation (AF) is associated with electrical and structural
remodeling. The aim of this study was to assess the contribution of electrical and structural …

Hypertension and cardiac arrhythmias: a review of the epidemiology, pathophysiology and clinical implications

KH Yiu, HF Tse - Journal of human hypertension, 2008 - nature.com
Hypertension is commonly associated with cardiac arrhythmias in patients with and without
concomitant cardiovascular disease. Experimental and epidemiological studies have …

The role of angiotensin receptor blockers and/or angiotensin converting enzyme inhibitors in the prevention of atrial fibrillation in patients with cardiovascular diseases …

AH Madrid, J Peng, J Zamora, I Marín… - Pacing and clinical …, 2004 - Wiley Online Library
The inhibition of the renin‐angiotensin system has demonstrated both experimental and
clinical effects in preventing atrial fibrillation. However, there is still uncertainty about the role …

Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation

D Darbar, AA Motsinger, MD Ritchie, JV Gainer… - Heart Rhythm, 2007 - Elsevier
BACKGROUND: The angiotensin-converting enzyme (ACE) deletion allele, ACE D, is
associated with increased ACE activity and adverse outcomes in cardiovascular disease …

Impact of ramipril on the incidence of atrial fibrillation: results of the Heart Outcomes Prevention Evaluation study

O Salehian, J Healey, B Stambler, K Alnemer… - American heart …, 2007 - Elsevier
OBJECTIVES: We evaluated the effect of angiotensin-converting enzyme (ACE) inhibitor
ramipril on the incidence of atrial fibrillation (AF) in patients enrolled in the Heart Outcomes …

Atrial fibrillation: mechanistic insights and treatment options

ST Mathew, J Patel, S Joseph - European journal of internal medicine, 2009 - Elsevier
Atrial fibrillation (AF) remains the most common clinically encountered arrhythmia. Unlike
supraventricular arrhythmias that use a defined mechanism, AF involves a wide spectrum of …

Cardiac arrhythmias in arterial hypertension

D Varvarousis, M Kallistratos… - The Journal of …, 2020 - Wiley Online Library
Patients with arterial hypertension frequently manifest various cardiac rhythm disturbances,
ranging from bradyarrhythmias to supraventricular premature beats, atrial fibrillation, or other …

Effect of renal sympathetic denervation on the inducibility of atrial fibrillation during rapid atrial pacing

Q Zhao, S Yu, M Zou, Z Dai, X Wang, J Xiao… - Journal of interventional …, 2012 - Springer
Background Atrial fibrillation (AF) is associated with activity of renin–angiotensin–
aldosterone system (RAAS). Reduction in renal noradrenaline spillover could be achieved …

Genetic variants associated with risk of atrial fibrillation regulate expression of PITX2, CAV1, MYOZ1, C9orf3 and FANCC

RIR Martin, MS Babaei, MK Choy, WA Owens… - Journal of molecular and …, 2015 - Elsevier
Genome-wide association studies (GWAS) have identified genetic variants in a number of
chromosomal regions that are associated with atrial fibrillation (AF). The mechanisms …

Contemporary management of atrial fibrillation: update on anticoagulation and invasive management strategies

MA Crandall, DJ Bradley, DL Packer… - Mayo Clinic …, 2009 - Elsevier
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. Its
increasing prevalence, particularly among the elderly, renders it one of the most serious …