Role of HMGB1/TLR4 and IL-1β/IL-1R1 signaling pathways in epilepsy

S Zhang, F Chen, F Zhai, S Liang - Frontiers in Neurology, 2022 - frontiersin.org
Epilepsy is a chronic disorder of the nervous system characterized by recurrent seizures.
Inflammation is one of the six major causes of epilepsy, and its role in the pathogenesis of …

In what ways does health related stigma affect sustainable employment and well-being at work? A systematic review

IE Van Beukering, SJC Smits, KME Janssens… - Journal of occupational …, 2021 - Springer
Purpose Studies are increasingly showing that health related stigma is a barrier to
employment, but it is not known how. The aim of this systematic review is to identify …

Neuropsychiatric and cognitive comorbidities in epilepsy

M Mula, H Coleman, SJ Wilson - CONTINUUM: Lifelong Learning …, 2022 - journals.lww.com
Neuropsychiatric and Cognitive Comorbidities in Epilepsy : CONTINUUM: Lifelong
Learning in Neurology Account Register Activate Subscription Help Subscribe American …

Epilepsy and attention deficit hyperactivity disorder: connection, chance, and challenges

HC Fan, KL Chiang, KH Chang, CM Chen… - International Journal of …, 2023 - mdpi.com
Comorbidities are common in children with epilepsy, with nearly half of the patients having
at least one comorbidity. Attention deficit hyperactivity disorder (ADHD) is a psychiatric …

Nanodelivery systems as a promising therapeutic potential for epilepsy: Current status and future perspectives

A Movahedpour, R Taghvaeefar… - CNS Neuroscience …, 2023 - Wiley Online Library
Epilepsy is a common chronic neurological disorder caused by aberrant neuronal electrical
activity. Antiseizure medications (ASMs) are the first line of treatment for people with …

Potential neuroprotective effect of the HMGB1 inhibitor glycyrrhizin in neurological disorders

YN Paudel, E Angelopoulou, B Semple… - ACS chemical …, 2020 - ACS Publications
Glycyrrhizin (glycyrrhizic acid), a bioactive triterpenoid saponin constituent of Glycyrrhiza
glabra, is a traditional medicine possessing a plethora of pharmacological anti-inflammatory …

Gender and socioeconomic disparities in global burden of epilepsy: an analysis of time trends from 1990 to 2017

Y Hu, Y Shan, Q Du, Y Ding, C Shen, S Wang… - Frontiers in …, 2021 - frontiersin.org
Objective: The objective of the study is to investigate the gender and socioeconomic
disparities in the global burden of epilepsy by prevalence and disability-adjusted life-years …

High mobility group box 1 (HMGB 1) as a novel frontier in epileptogenesis: from pathogenesis to therapeutic approaches

YN Paudel, BD Semple, NC Jones… - Journal of …, 2019 - Wiley Online Library
Epilepsy is a serious neurological condition exhibiting complex pathology and deserving of
more serious attention. More than 30% of people with epilepsy are not responsive to more …

Mortality, and life expectancy in Epilepsy and Status epilepticus—current trends and future aspects

E Trinka, LJ Rainer, CA Granbichler… - Frontiers in …, 2023 - frontiersin.org
Patients with epilepsy carry a risk of premature death which is on average two to three times
higher than in the general population. The risk of death is not homogenously distributed over …

Time–frequency statistical features of delta band for detection of epileptic seizures

M Sameer, B Gupta - Wireless Personal Communications, 2022 - Springer
Various research groups are working on the automated detection of epileptic seizures using
Electroencephalogram (EEG) data. EEG waveforms are composed of distinct bands of …