Urinary tract infection (UTI), an infection anywhere in the urinary tract (urethra, bladder,
ureters, or kidneys) is very common. In 2007 in the United States there were 10.5 million …

Antibiotic treatment failure is of growing concern. Genetically encoded resistance is key in
driving this process. However, there is increasing evidence that bacterial antibiotic …

Escherichia coli is a paradigm for a versatile bacterial species which comprises harmless
commensal as well as different pathogenic variants with the ability to either cause intestinal …

Extra-intestinal pathogenic Escherichia coli (ExPEC) have a complex phylogeny, broad
virulence factor (VF) armament and significant genomic plasticity, and are associated with a …

Bacterial virulence is highly dynamic and context-dependent. For this reason, it is
challenging to predict how molecular changes affect the growth of a pathogen in a host and …

Abstract Background. Fluoroquinolone-resistant Escherichia coli are increasingly prevalent.
Their clonal origins—potentially critical for control efforts—remain undefined. Methods …

Chronic lower urinary tract symptoms (LUTS), such as urgency and incontinence, are
common, especially among the elderly, but their etiology is often obscure. Recent studies of …

Urinary tract infection is among the most common infections worldwide, typically studied in
animals and cell lines with limited uropathogenic strains. Here, we assessed diverse …

In this work we report synthetic adhesins (SAs) enabling the rational design of the adhesion
properties of E. coli. SAs have a modular structure comprising a stable β-domain for outer …

Background/Purpose The clinical aspects of virulence genes of uropathogenic Escherichia
coli (UPEC) are not fully understood. This study compared the presence of virulence genes …