[HTML][HTML] Advances in anti-inflammatory medicinal plants and phytochemicals in the management of arthritis: A comprehensive review

Y Gandhi, R Kumar, J Grewal, H Rawat… - Food chemistry …, 2022 - Elsevier
Rheumatoid arthritis (RA) is considered to be an inflammatory disorder whereas OA is not
an overtly inflammatory disorder as RA but certain inflammatory cytokines and periodic …

Towards a better understanding of Fagopyrum dibotrys: a systematic review

LL Zhang, Y He, F Sheng, YF Hu, Y Song, W Li… - Chinese Medicine, 2021 - Springer
Abstract Fagopyrum dibotrys (F. dibotrys)(D. Don) H. Hara is a well-known edible herbal
medicine in Asian countries. It has been widely used for the treatment of lung diseases …

The protective effect of protocatechuic acid on hepatotoxicity induced by cisplatin in mice

SA Habib, GM Suddek, MA Rahim, RS Abdelrahman - Life sciences, 2021 - Elsevier
Cisplatin is one of the most potent anti-cancer drugs used for the treatment of various solid
tumors, yet it has several side effects that may limit its clinical use. Hepatotoxicity is one of …

[HTML][HTML] Construction of MOFs nanoplatform with pH-triggered release of protocatechuic acid for intervertebral disc degeneration therapy

H Ding, X Zhang, Z Liu, J Wang, C Zhu, Q Chen… - Materials & Design, 2023 - Elsevier
Lower back pain is a significant contributor to disability and incapacity in adults. Up to 40%
of lower back pain is considered to be caused primarily by disc degeneration. The pH value …

MicroRNA-137-mediated inhibition of lysine-specific demethylase-1 prevents against rheumatoid arthritis in an association with the REST/mTOR axis

W Sun, Y Zhang, G Wang - Molecular Pain, 2021 - journals.sagepub.com
Background It has been increasingly reported that microRNAs (miRNAs) are related to
rheumatoid arthritis (RA) pathogenesis. This present research was conducted to analyze the …

Ethyl Protocatechuate Encapsulation in Solid Lipid Nanoparticles: Assessment of Pharmacotechnical Parameters and Preliminary In Vitro Evaluation for Colorectal …

S Russo, C Torrisi, N Cardullo, V Muccilli, A La Mantia… - Pharmaceutics, 2023 - mdpi.com
Colorectal cancer is one of the most diffused tumoral diseases. Since most medicaments
employed for its treatment are debilitating, the use of naturally derived products, which can …

Protocatechuic acid protects against thioacetamide-induced chronic liver injury and encephalopathy in mice via modulating mTOR, p53 and the IL-6/IL-17/IL-23 …

RS Abdelrahman, GS El-Tanbouly - Toxicology and Applied Pharmacology, 2022 - Elsevier
Protocatechuic acid (PCA), a natural phenolic acid, is known for antioxidant, anti-
inflammatory, anti-apoptotic, and anti-fibrotic activities. However, the protective mechanisms …

Lentivirus-mediated overexpression or silencing of aquaporin 1 affects the proliferation, migration and invasion of TNF-α-stimulated rheumatoid arthritis fibroblast-like …

M Zhou, L Cai, X Feng, Y Mu, B Meng… - Journal of Inflammation …, 2021 - Taylor & Francis
Introduction Previous studies have confirmed the pathologic role of synovial aquaporin 1
(AQP1) in rheumatoid arthritis (RA), but its associations with the abnormal biologic …

Agglomerated serum albumin adsorbed protocatechuic acid coated superparamagnetic iron oxide nanoparticles as a theranostic agent

S Bozoglu, MB Arvas, HS Varlı, B Ucar, T Acar… - …, 2023 - iopscience.iop.org
Iron oxide nanoparticles have been one of the most widely used nanomaterials in
biomedical applications. However, the incomplete understanding of the toxicity mechanisms …

Transcriptomic profiling revealed the role of apigenin-4′-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK …

D Cao, Q Fan, Z Li, M Chen, Y Jiang, R Lin, J Li… - Phytomedicine, 2022 - Elsevier
Background Activated fibroblast-like synoviocyte (FLS) played a significant role in the
pathogenesis and progression of rheumatoid arthritis (RA). Apigenin-4′-O-α-L-rhamnoside …