Impact of the host response and osteoblast lineage cells on periodontal disease

M Zhou, DT Graves - Frontiers in immunology, 2022 - frontiersin.org
Periodontitis involves the loss of connective tissue attachment and alveolar bone. Single cell
RNA-seq experiments have provided new insight into how resident cells and infiltrating …

The genetic aspects of periodontitis pathogenesis and the regenerative properties of stem cells

K Ustianowska, Ł Ustianowski, E Bakinowska… - Cells, 2024 - mdpi.com
Periodontitis (PD) is a prevalent and chronic inflammatory disease with a complex
pathogenesis, and it is associated with the presence of specific pathogens, such as …

Dynamic chromatin accessibility landscapes of osteoblast differentiation and mineralization

Y Chen, J Tan, C Yang, Z Ling, J Xu, D Sun… - Biochimica et Biophysica …, 2024 - Elsevier
Bone acts as a self-healing organ, which undergoes continuous regeneration process that is
tightly regulated by the cooperation of osteoclasts with the capability of bone resorption and …

Epigenetic regulation of osteogenic differentiation of periodontal ligament stem cells in periodontitis

J Cao, Q Zhang, Q Yang, Y Yu, M Meng, J Zou - Oral Diseases, 2023 - Wiley Online Library
Periodontitis is an inflammatory disease characterized by alveolar bone loss. Periodontal
ligament stem cells (PDLSCs) have osteogenic differentiation potential, which can be …

Molecular research on oral diseases and related biomaterials: A journey from oral cell models to advanced regenerative perspectives

T Steinberg, MP Dieterle, P Tomakidi - International Journal of Molecular …, 2022 - mdpi.com
Oral diseases such as gingivitis, periodontitis, and oral cancer affect millions of people
worldwide. Much research has been conducted to understand the pathogenetic …

Roles of DNA methylation in influencing the functions of dental‐derived mesenchymal stem cells

L Shi, X Ye, J Zhou, Y Fang, J Yang, M Meng… - Oral …, 2024 - Wiley Online Library
Objective DNA methylation as intensively studied epigenetic regulatory mechanism exerts
pleiotropic effects on dental‐derived mesenchymal stem cells (DMSCs). DMSCs have self …

DNA methylation and its potential roles in common oral diseases

H Liu, L Ma, Z Cao - Life Sciences, 2024 - Elsevier
Oral diseases are among the most common diseases worldwide and are associated with
systemic illnesses, and the rising occurrence of oral diseases significantly impacts the …

[HTML][HTML] Osteogenic differentiation of periodontal ligament fibroblasts inhibits osteoclast formation

CM Prins, M Ceylan, JMA Hogervorst… - European Journal of …, 2024 - Elsevier
One of the deficits of knowledge on bone remodelling, is to what extent cells that are driven
towards osteogenic differentiation can contribute to osteoclast formation. The periodontal …

Evaluation of the effect of auto-transplanted tooth for repairing maxillary sinus perforation compared to traditional flap repair

F Liao, B Zhang, H Zhong - medRxiv, 2024 - medrxiv.org
Objective: The purpose of this study is to compare the outcomes of using auto-transplanted
tooth and flap for repairing sinus perforation after tooth extraction. The aim is to provide a …

Analyzes in silico indicate the lncRNAs MIR31HG and LINC00939 as possible epigenetic inhibitors of the osteogenic differentiation in PDLCs

RS Ferreira, RIF Assis, F Racca, AC Bontempi… - Genes, 2023 - mdpi.com
Chromatin conformation, DNA methylation pattern, transcriptional profile, and non-coding
RNAs (ncRNAs) interactions constitute an epigenetic pattern that influences the cellular …