Metabolomics is the discipline where endogenous and exogenous metabolites are
assessed, identified and quantified in different biological samples. Metabolites are crucial …

Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …

OBJECTIVE Many guidelines recommend reduced consumption of salt in patients with type
1 diabetes, but it is unclear whether dietary sodium intake is associated with mortality and …

Patients with type 1 diabetes mellitus (T1DM) traditionally had a low body mass index and
microangiopathic complications were common, while macroangiopathy and the metabolic …

Context: Circulating microRNAs (miRNAs/miRs) are used as novel biomarkers for diseases.
miR-21, miR-126, and miR-210 are known to be deregulated in vivo or in vitro under …

Diabetic kidney disease (DKD) is a devastating complication that affects an estimated third
of patients with type 1 diabetes mellitus (DM). There is no cure once the disease is …

With a global prevalence of 9%, diabetes is the direct cause of millions of deaths each year
and is quickly becoming a health crisis. Major long-term complications of diabetes arise from …

Aims/hypothesis Lipid abnormalities are associated with diabetic kidney disease and CHD,
although their exact role has not yet been fully explained. Sphingomyelin, the predominant …

Patients with both type 1 diabetes and CKD have an increased risk of adverse outcomes.
The competing risks of death and ESRD may confound the estimates of risk for each …

Diabetic peripheral neuropathy is the most common complication of diabetes and a source
of considerable morbidity. Numerous molecular pathways are linked to neuropathic …