There is growing consensus that certain lifestyles can contribute to cognitive impairment and
dementia, but the physiological steps that link a harmful lifestyle to its negative impact are …

Cognitive frailty (CF) is a clinical condition defined by the presence of both mild cognitive
impairment (MCI) and physical frailty (PF). Elderly with CF are at greater risk of dementia …

A considerable complication for stroke survivors is the subsequent development of cognitive
decline or dementia. In this study, the relationship between the inflammation-centered …

Background: Recent studies have demonstrated increased microglial activation using 11C-
PK11195 positron emission tomography imaging, indicating central nervous system …

Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …

The major vascular cause of dementia is cerebral small vessel disease (SVD), including
white matter hyperintensities (WMH) amongst others. While the underlying pathology of SVD …

The inflammatory response is a major pathological feature in most kidney diseases and
often evokes compensatory mechanisms. Recent evidence suggests that TSG-6 (tumor …

Background This study aimed to explore the association between deep medullary veins
(DMVs) and the neuroimaging burden of cerebral small vessel disease (CSVD). Methods In …

Dementia has been faced with significant public health challenges and economic burdens
that urges the need to develop safe and effective interventions. In recent years, an …

Background Chronic inflammation might play a major role in the pathogenesis linking
diabetes mellitus (DM) to cognition. In addition, DM might be the main driver of dementia …