Background Significant pain can be experienced after laparoscopic cholecystectomy. This
systematic review aims to formulate PROSPECT (PROcedure SPECific Postoperative Pain …

This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Background The attempt to further reduce operative trauma in laparoscopic cholecystectomy
has led to new techniques such as natural orifice transluminal endoscopic surgery (NOTES) …

Pain relief after laparoscopic cholecystectomy (LC) is an issue of great practical importance.
Pain after LC has several origins: incisional, local visceral, peritoneal, and referred. Several …

Wound infiltration with local anaesthetics is a simple, effective and inexpensive means of
providing good analgesia for a variety of surgical procedures without any major side‐effects …

Background Different regional anesthesia (RA) techniques have been used for laparoscopic
cholecystectomy (LC), but there is no consensus on their comparative effectiveness. Our …

Background/purpose With the advent of minimally invasive gallbladder surgery, and now
with natural orifice techniques emerging, visceral nociception has been neglected as a …

AIM: To systematically evaluate the effect of intraperitoneal local anesthetic on pain
characteristics after laparoscopic cholecystectomy (LC). METHODS: We searched …

Background A clinical trial was designed to assess the use of preincisional and
intraperitoneal ropivacaine, combined or not with normal saline, to reduce pain after …

Aim: The aim of this study was to determine the effect of sodium bicarbonate irrigation versus
normal saline irrigation in patients undergoing a laparoscopic cholecystectomy …