Regulation of the hypoxia-inducible factor (HIF) by pro-inflammatory cytokines
Hypoxia and inflammation are frequently co-incidental features of the tissue
microenvironment in a wide range of inflammatory diseases. While the impact of hypoxia on …
microenvironment in a wide range of inflammatory diseases. While the impact of hypoxia on …
Ghrelin as a promising therapeutic option for cancer cachexia
MN Khatib, A Gaidhane, S Gaidhane… - Cellular Physiology and …, 2018 - karger.com
Cachexia is a devastating complication of cancer and an important cause of morbidity and
mortality and can have a great effect on quality of life, and sense of self-esteem …
mortality and can have a great effect on quality of life, and sense of self-esteem …
The inflammatory burden index is a superior systemic inflammation biomarker for the prognosis of non‐small cell lung cancer
Background Systemic inflammation, the most representative tumour–host interaction, plays a
crucial role in disease progression and prognosis in patients with non‐small cell lung cancer …
crucial role in disease progression and prognosis in patients with non‐small cell lung cancer …
Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patients
EE Talbert, HL Lewis, MR Farren… - Journal of cachexia …, 2018 - Wiley Online Library
Background Cancer‐associated wasting, termed cancer cachexia, has a profound effect on
the morbidity and mortality of cancer patients but remains difficult to recognize and …
the morbidity and mortality of cancer patients but remains difficult to recognize and …
Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia–can findings from animal models be translated to humans?
TC Mueller, J Bachmann, O Prokopchuk, H Friess… - BMC cancer, 2016 - Springer
Background Cachexia is a multi-factorial, systemic syndrome that especially affects patients
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
with cancer of the gastrointestinal tract, and leads to reduced treatment response, survival …
Cachexia‐associated adipose tissue morphological rearrangement in gastrointestinal cancer patients
Background and aims Cachexia is a syndrome characterized by marked involuntary loss of
body weight. Recently, adipose tissue (AT) wasting has been shown to occur before the …
body weight. Recently, adipose tissue (AT) wasting has been shown to occur before the …
Comprehensive comparison of the prognostic value of systemic inflammation biomarkers for cancer cachexia: a multicenter prospective study
Aims Systemic inflammation plays an important role in cancer cachexia. However, among
the systemic inflammatory biomarkers, it is unclear which has optimal prognostic value for …
the systemic inflammatory biomarkers, it is unclear which has optimal prognostic value for …
[HTML][HTML] Adipose tissue-derived factors as potential biomarkers in cachectic cancer patients
ML Batista Jr, M Olivan, PSM Alcantara, R Sandoval… - Cytokine, 2013 - Elsevier
Cachexia, a paraneoplastic syndrome markedly associated with worsened prognosis in
cancer patients, provokes profound wasting of both lean and adipose mass in an …
cancer patients, provokes profound wasting of both lean and adipose mass in an …
Cancer as a proinflammatory environment: metastasis and cachexia
N Inácio Pinto, J Carnier, LM Oyama… - Mediators of …, 2015 - Wiley Online Library
The development of the syndrome of cancer cachexia and that of metastasis are related with
a poor prognostic for cancer patients. They are considered multifactorial processes …
a poor prognostic for cancer patients. They are considered multifactorial processes …
Exercise training as treatment in cancer cachexia
Cachexia is a wasting syndrome that may accompany a plethora of diseases, including
cancer, chronic obstructive pulmonary disease, aids, and rheumatoid arthritis. It is …
cancer, chronic obstructive pulmonary disease, aids, and rheumatoid arthritis. It is …