Cranial sutures are dynamic structures in which stem cell biology, bone formation, and
mechanical forces interface, influencing the shape of the skull throughout development and …

Glioma-associated oncogene homolog 1 (Gli1) is a transcriptional activator of hedgehog
(Hh) signaling that regulates target gene expression and several cellular biological …

The meninges lie in the interface between the skull and brain, harboring lymphatic
vasculature and skull progenitor cells (SPCs). How the skull and brain communicate …

Skull development coincides with the onset of cerebrospinal fluid (CSF) circulation, brain-
CSF perfusion, and meningeal lymphangiogenesis, processes essential for brain waste …

The spatial and temporal development of the brain, overlying meninges (fibroblasts,
vasculature and immune cells) and calvarium are highly coordinated. In particular, the timing …

Nickel, a common environmental hazard, is a risk factor for craniosynostosis. However, the
underlying biological mechanism remains unclear. Here, we found that early-life nickel …

To present the outcomes and adverse events associated with the endoscopic-assisted,
minimally invasive suturectomy in patients with multisuture synostosis. This retrospective …

Background In recent times, stem cell therapy has recently gained popularity, and is used for
regenerating oral and maxillofacial structures. This study aimed to review stem cell …

Disruption of global ribosome biogenesis selectively affects craniofacial tissues with unclear
mechanisms. Craniosynostosis is a congenital craniofacial disorder characterized by …

The calvaria (top part of the skull) is made of pieces of bone as well as multiple soft tissue
joints called sutures. The latter is crucial to the growth and morphogenesis of the skull, and …