The global burden of neurological disorders is substantial and increasing, especially in low-
resource settings. The current increased global interest in brain health and its impact on …

Gene–environment interactions begin at conception to influence maternal/placental/fetal
triads, neonates, and children with short-and long-term effects on brain development. Life …

Background Disorders affecting the nervous system are diverse and include
neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions …

Abstract Development of effective therapeutics for neurological disorders has historically
been challenging partly because of lack of accurate model systems in which to investigate …

Importance The risk of epilepsy after neonatal invasive Group BStreptococcus (iGBS)
disease, particularly iGBS sepsis, is poorly understood. Objective To examine the …

Background: Neurological impairment (NI) and disability are associated with reduced life
expectancy, but the risk and magnitude of premature mortality in children vary considerably …

Objectives Socioeconomic factors play a role in the outcome of chronic diseases in
childhood. Epilepsy is the most common chronic neurological disease in childhood. The …

Neonatal encephalopathy is a leading cause of morbidity and mortality worldwide. Although
therapeutic hypothermia (HT) is now standard practice in most neonatal intensive care units …

Abstract Global estimates show that 10–20% of persons express developmental disability.
During critical and sensitive periods of developmental neuroplasticity over the first 1000 …

Se estima que el 96% de los recién nacidos (RN) con encefalopatía hipóxico-isquémica
(EHI) nacen en entornos con recursos limitados (ERL) sin capacidad para ofrecer el …