The role of micronutrients in support of the immune response against viral infections

F Pecora, F Persico, A Argentiero, C Neglia, S Esposito - Nutrients, 2020 - mdpi.com
Viral infections are a leading cause of morbidity and mortality worldwide, and the importance
of public health practices including handwashing and vaccinations in reducing their spread …

The interplay between vitamin D and viral infections

M Teymoori‐Rad, F Shokri, V Salimi… - Reviews in medical …, 2019 - Wiley Online Library
The pleiotropic role of vitamin D has been explored over the past decades and there is
compelling evidence for an epidemiological association between poor vitamin D status and …

[HTML][HTML] Vitamin D deficiency and air pollution exacerbate COVID-19 through suppression of antiviral peptide LL37

MA Crane-Godreau, KJ Clem, P Payne… - Frontiers in public …, 2020 - frontiersin.org
Vitamin D deficiency and insufficiency (VDD) are widely recognized as risk factors for
respiratory tract infections. Vitamin D influences expression of many genes with well …

Controversial effects of vitamin D and related genes on viral infections, pathogenesis, and treatment outcomes

C Lee - Nutrients, 2020 - mdpi.com
Vitamin D (VD) plays an essential role in mineral homeostasis and bone remodeling. A
number of different VD-related genes (VDRG) are required for the metabolic activation of VD …

Vitamin D modulates expression of antimicrobial peptides and proinflammatory cytokines to restrict Zika virus infection in macrophages

GJ Fernandez, JM Ramírez-Mejía, JA Castillo… - International …, 2023 - Elsevier
Although the impact of Zika virus (ZIKV) infection on human health has been well
documented, we still have no vaccine or effective treatment. This fact highlights the …

Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

TJM Gonçalves, SEAB Gonçalves, A Guarnieri… - Clinical nutrition …, 2020 - Elsevier
Background & aim Verify the prevalence of hypovitaminosis D and obesity in elderly patients
infected by new coronavirus. The patients developed severe symptoms and were admitted …

Vitamin D enhances type I IFN signaling in COVID-19 patients

S Hafezi, F Saheb Sharif-Askari… - Scientific Reports, 2022 - nature.com
The ability of Vitamin D (VitD) to modulate antiviral responses through induction of
antimicrobial peptide is well established. However, the effect of VitD on host responses to …

Vitamin D modulates inflammatory response of DENV-2-infected macrophages by inhibiting the expression of inflammatory-liked miRNAs

JA Castillo, S Urcuqui-Inchima - Pathogens and Global Health, 2023 - Taylor & Francis
Dengue disease caused by dengue virus (DENV) infection is the most common vector-borne
viral disease worldwide. Currently, no treatment is available to fight dengue symptoms. We …

Vitamin D Deficiency (VDD) and Susceptibility towards Severe Dengue Fever—A Prospective Cross-Sectional Study of Hospitalized Dengue Fever Patients from …

S Iqtadar, A Khan, SU Mumtaz, S Livingstone… - Tropical medicine and …, 2023 - mdpi.com
Dengue is a mosquito-borne flaviviral serious febrile illness, most common in the tropical
and subtropical regions including Pakistan. Vitamin D is a strong immunomodulator affecting …

Regulation of innate immune responses in macrophages differentiated in the presence of vitamin D and infected with dengue virus 2

JA Castillo, DM Giraldo, JC Hernandez… - PLOS Neglected …, 2021 - journals.plos.org
A dysregulated or exacerbated inflammatory response is thought to be the key driver of the
pathogenesis of severe disease caused by the mosquito-borne dengue virus (DENV) …