[HTML][HTML] Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression

Y Tanaka, M Eizuka, N Uesugi, K Kawasaki… - Journal of …, 2020 - Springer
Background Recent studies have shown that traditional serrated adenoma (TSA) can be
classified into BRAF and KRAS subtypes. Here, we examined the clinicopathological and …

A morphological and molecular study of proposed early forms of traditional serrated adenoma

M Bettington, C Rosty, V Whitehall, B Leggett… - …, 2018 - Wiley Online Library
Aims Traditional serrated adenoma (TSA) is the least common subtype of serrated colorectal
polyp. Large protuberant lesions are easily recognised; however, the origins of TSAs are not …

Macroscopic and microscopic morphology and molecular profiling to distinguish heterogeneous traditional serrated adenomas of the colorectum

A Chino, H Kawachi, M Takamatsu… - Digestive …, 2020 - Wiley Online Library
Objectives Serrated lesions of the colorectum often have complex histological morphology,
and some groups include subtypes with different molecular biology. This study aimed to …

Endoscopic features of isolated and traditional serrated adenoma‐associated superficially serrated adenomas of the colorectum

Y Mizuguchi, Y Tanaka, H Cho, M Sekiguchi… - Digestive …, 2022 - Wiley Online Library
Background and Aim Superficially serrated adenoma (SuSA) is a recently proposed subtype
of colorectal serrated lesions. It is characterized by distinct clinicopathological and molecular …

Prevalence of serrated lesions, risk factors, and their association with synchronous advanced colorectal neoplasia in asymptomatic screened individuals

M Sekiguchi, Y Kakugawa, M Matsumoto… - Journal of …, 2020 - Wiley Online Library
Abstract Background and Aim Serrated lesions (SLs) have attracted attention as precursors
of colorectal cancer (CRC). However, their prevalence, risk factors, and clinical significance …

Endoscopic features with associated histological and molecular alterations in serrated polyps with dysplasia: Retrospective analysis of a tertiary case series

A Trecca, R Borghini, D Medicina, R Del Sordo… - Digestive and Liver …, 2024 - Elsevier
Background Serrated polyps are incompletely understood lesions and include serrated
sessile lesion (SSL) without or with dysplasia and traditional serrated adenoma (TSA). Aims …

Non-coding RNAs in Precursor Lesions of Colorectal Cancer: Their Role in Cancer Initiation and Formation

S Mohammadpour, FN Noukabadi… - Current Molecular …, 2024 - ingentaconnect.com
Colorectal cancer (CRC) is one of the world's most common types of malignancy. The
proliferation of precancerous lesions causes this type of cancer. Two distinct pathways for …

Clinicopathological and molecular analyses of hyperplastic lesions including microvesicular variant and goblet cell rich variant hyperplastic polyps and hyperplastic …

N Uesugi, Y Ajioka, T Arai, Y Tanaka… - Pathology …, 2022 - Wiley Online Library
Hyperplastic nodules (HNs) have been considered to be hyperplastic lesions among
Japanese pathologists, although they have not been recognized worldwide. Here, we …

Superficially serrated adenoma: Novel precursor in the serrated pathway

K Togashi - Dig Endosc, 2022 - search.ebscohost.com
The authors also focus on SuSAs accompanied by TSAs alone, but we should look at
tubular adenomas, villous adenomas, invasive cancers, and miscellaneous lesions as …

[HTML][HTML] Superficial Serrated Adenoma (SuSA): A New Subtype of Serrated Lesions

R Chen, Q Zhang - Journal of Biosciences and Medicines, 2024 - scirp.org
Superficial serrated adenoma (SuSA) is a new subtype of serrated lesions proposed in
recent years, most of which are located in the sigmoid colon or rectum, with typical mixed …