Background Ulcerative colitis (UC) is a chronic, unspecific inflammatory bowel disorder
lacking effective therapeutic targets and radical drugs. Oxyberberine (OBB), a novel …

Background Traumatic brain injury (TBI) is known as a silent epidemic that causes many
deaths and disabilities worldwide. We examined the response of oxyberberine (OBB) in …

Colorectal cancer (CRC) is a common digestive tract tumor, with incidences continuing to
rise. Although modern medicine has extended the survival time of CRC patients, its adverse …

Reactive oxygen species (ROS) are highly reactive molecules generated in living organisms
and an excessive production of ROS culminates in oxidative stress and cellular damage …

5-fluorouracil (5-FU) is one of the most widely used chemotherapy drugs for malignant
tumors. However, intestinal mucositis caused by 5-FU is a severe dose-limiting toxic effect …

This study aims to evaluate the effect of berberine-based carbon quantum dots (Ber-CDs) on
improving 5-fluorouracil (5-FU)-induced intestinal mucositis in C57BL/6 mice, and explored …

Previous studies have shown that oxyberberine (OBB), a novel gut microbiota metabolite of
berberine, exhibited prominent protective property against acute liver injury and non …

Anticancer drugs exhibit many side effects, including skin pigmentation, which often lowers
patient QOL. However, the mechanism of pigmentation caused by anticancer drugs remains …

Intestinal mucositis (IM) is a common side effect of several anticancer medications, including
5-fluorouracil (5-FU), and can lead to treatment disruptions and compromised outcomes. IM …

The intestinal mucositis is defined as the inflammation and ulceration in the-gastrointestinal
tract wall and in some case in the-oral cavity that can be caused by treatment with …