Cadmium in food: Source, distribution and removal

R Wang, P Sang, Y Guo, P Jin, Y Cheng, H Yu, Y Xie… - Food Chemistry, 2023 - Elsevier
Since its discovery, cadmium (Cd) has played an important role in industry and brought
certain conveniences to mankind, used for electroplating and making rechargeable …

Mechanisms of cadmium-induced testicular injury: a risk to male fertility

W Ali, Y Ma, J Zhu, H Zou, Z Liu - Cells, 2022 - mdpi.com
Cadmium is a heavy toxic metal with unknown biological functions in the human body. Over
time, cadmium accretion in the different visceral organs (liver, lungs, kidney, and testis) is …

Effects of cadmium, lead, and mercury on the structure and function of reproductive organs

P Massányi, M Massányi, R Madeddu, R Stawarz… - Toxics, 2020 - mdpi.com
Reproductive organs are essential not only for the life of an individual but also for the
survival and development of the species. The response of reproductive organs to toxic …

[HTML][HTML] Evidence of melatonin ameliorative effects on the blood-testis barrier and sperm quality alterations induced by cadmium in the rat testis

M Venditti, MB Rhouma, MZ Romano… - Ecotoxicology and …, 2021 - Elsevier
Herein, we further document the protective action of melatonin (MLT) in mitigating cadmium
(Cd) effects on adult rat testis. Cd treatment provoked testicular injury, that was documented …

[HTML][HTML] Cadmium-induced cytotoxicity: effects on mitochondrial electron transport chain

JJV Branca, A Pacini, M Gulisano, N Taddei… - Frontiers in cell and …, 2020 - frontiersin.org
Cadmium (Cd) is a well-known heavy metal and environmental toxicant and pollutant
worldwide, being largely present in every kind of item such as plastic (toys), battery, paints …

[HTML][HTML] Apoptosis, inflammation, and oxidative stress in infertility: A mini review

OA Ojo, PI Nwafor-Ezeh, DE Rotimi, M Iyobhebhe… - Toxicology Reports, 2023 - Elsevier
Infertility has been a major issue in our society for many years, and millions of couples all
over the world are still experiencing it. There are several reasons for and causes of infertility …

Cadmium attenuates testosterone synthesis by promoting ferroptosis and blocking autophagosome-lysosome fusion

L Zeng, J Zhou, X Wang, Y Zhang, M Wang… - Free Radical Biology and …, 2021 - Elsevier
Ferroptosis is a newly defined programmed cell death pathway characterized by iron
overload and lipid peroxidation. Increasing studies show that autophagy regulates …

Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway

J Zhou, L Zeng, Y Zhang, M Wang, Y Li, Y Jia… - Science of The Total …, 2022 - Elsevier
High doses of cadmium (Cd) cause irreversible injury to the reproductive system, especially
testicular tissue. Studies have shown that pyroptosis is involved in Cd-induced tissue …

Effect of heavy metals on epididymal morphology and function: An integrative review

M Machado-Neves - Chemosphere, 2022 - Elsevier
Male fertility has deteriorated over the last decades, and environmental risk factors are
among the possible causes of this phenomenon. Pollutants such as heavy metals might …

Cadmium-induced apoptosis of Leydig cells is mediated by excessive mitochondrial fission and inhibition of mitophagy

L Yi, XJ Shang, L Lv, Y Wang, J Zhang, C Quan… - Cell Death & …, 2022 - nature.com
Cadmium is one of the environmental and occupational pollutants and its potential adverse
effects on human health have given rise to substantial concern. Cadmium causes damage to …