Immortalized cell lines are widely used in vitro tools in oncology and hematology research.
While these cell lines represent artificial systems and may accumulate genetic aberrations …

Simple Summary Cancer is the prime cause of death globally. The altered stimulation of
signaling pathways controlled by human kinases has often been observed in various human …

Apigenin is a dietary polyphenol found abundantly in fruit and vegetables, which sensitizes
leukaemia cells to topoisomerase inhibitor agents (eg, etoposide), and alkylating agents (eg …

Novel targets are constantly sought to fight hematologic malignancies. In this regard, high
levels of SIRT2 expression are associated with unfavorable prognosis of acute myeloid …

Acute myeloid leukemia (AML) represents the most alarming hematological disease for
adults. Several genetic modifications are known to be pivotal in AML; however, SIRT2 over …

The issue of food contamination by aflatoxins presently constitutes a social emergency,
since they represent a severe risk for human and animal health. On the other hand, the use …

Abstract Ethnopharmacological relevance Ganoderma lucidum (Curtis) P. Karst.(also known
as Linghzhi and Reishi) is the most appreciated and revered medicinal mushroom across …

Nanoparticles synthesized from biopolymers have received attention for their use as
biological carriers in the delivery of hydrophobic drugs. Alginate, a marine biopolymer, is …

Leukaemia is a malignant disease of the blood. Current treatments for leukaemia are
associated with serious side-effects. Plant-derived polyphenols have been identified as …

Leukemia is a type of blood cancer caused by the rapid proliferation of abnormal white
blood cells. Currently, several treatment options, including chemotherapy, radiation therapy …