[HTML][HTML] Defective gap junctional intercellular communication in the carcinogenic process

M Mesnil, S Crespin, JL Avanzo… - Biochimica et Biophysica …, 2005 - Elsevier
Gap junctions are membrane structures made of intercellular channels which permit the
diffusion from cytoplasm to cytoplasm of small hydrophilic molecules. Nearly 40 years ago …

Downregulation of gap junctions in cancer cells

E Leithe, S Sirnes, Y Omori… - Critical Reviews™ in …, 2006 - dl.begellhouse.com
Gap junctions are intercellular plasma membrane domains enriched in channels that allow
direct exchange of ions and small molecules between adjacent cells. Gap junction channels …

Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy

O Kucuk, FH Sarkar, W Sakr, Z Djuric, MN Pollak… - … Biomarkers & Prevention, 2001 - AACR
An inverse association has been observed between dietary intake of lycopene and the risk
of prostate cancer. We investigated the effects of lycopene supplementation in patients with …

Unique features of the basal cells of human prostate epithelium

M El‐Alfy, G Pelletier, LS Hermo… - … research and technique, 2000 - Wiley Online Library
The prostate gland is globally composed of epithelium and stroma. The epithelium plays an
important role in the development of both benign and malignant disorders while the stroma …

Lycopene in cancer prevention and treatment

S Seren, R Lieberman, UD Bayraktar… - American journal of …, 2008 - journals.lww.com
Dietary intake of lycopene is inversely associated with the risk of many cancers. Preclinical
studies show that lycopene has potent in vitro and in vivo antitumor effects, suggesting …

[HTML][HTML] Gap junctional communication in the male reproductive system

G Pointis, C Fiorini, N Defamie, D Segretain - Biochimica et Biophysica Acta …, 2005 - Elsevier
Male fertility is a highly controlled process that allows proliferation, meiosis and
differentiation of male germ cells in the testis, final maturation in the epididymis and also …

[HTML][HTML] Impaired gap junction connexin43 in Sertoli cells of patients with secretory azoospermia: a marker of undifferentiated Sertoli cells

N Defamie, I Berthaut, B Mograbi, D Chevallier… - Laboratory …, 2003 - nature.com
Gap junctions are intercellular channels formed of connexins (Cx) at appositional plasma
membranes between adjacent cells that have been involved in the control of cell …

Alterations in gap junction protein expression in human benign prostatic hyperplasia and prostate cancer

H Habermann, V Ray, W Habermann… - The Journal of …, 2002 - auajournals.org
Purpose: Gap junctions composed of connexin proteins have an essential role in
intercellular communication and differentiation. Dysregulation of connexin expression is …

Modulation of prostate cancer growth in bone microenvironments

M Edlund, SY Sung, LWK Chung - Journal of cellular …, 2004 - Wiley Online Library
Bone remains one of the major sites, and most lethal host organs, for prostate cancer
metastasis. Prostate cell spread and establishment in bone depends on multiple reciprocal …

The role of connexins in prostate cancer promotion and progression

J Czyż, K Szpak, Z Madeja - Nature Reviews Urology, 2012 - nature.com
Prostate cancer is a prevalent disease that is characterized by a presumably long latency
period and a moderate propensity to metastasize. Although a range of mechanisms have …