[PDF][PDF] Biosensor recognition elements

JP Chambers, BP Arulanandam, LL Matta… - Current issues in …, 2008 - mdpi.com
Molecular recognition is central to biosensing. Since the first biosensor was developed by
Updike and Hicks (1967) many biosensors have been studied and developed. As shown in …

The pivotal role of quantum dots-based biomarkers integrated with ultra-sensitive probes for multiplex detection of human viral infections

SM Mousavi, SA Hashemi, M Yari Kalashgrani… - Pharmaceuticals, 2022 - mdpi.com
The spread of viral diseases has caused global concern in recent years. Detecting viral
infections has become challenging in medical research due to their high infectivity and …

[HTML][HTML] Role of molecular chaperones in inclusion body formation

MM Carrió, A Villaverde - FEBS letters, 2003 - Elsevier
Protein misfolding and aggregation are linked to several degenerative diseases and are
responsible for the formation of bacterial inclusion bodies. Roles of molecular chaperones in …

Biosensors based on β-galactosidase enzyme: Recent advances and perspectives

SK Sharma, RM Leblanc - Analytical biochemistry, 2017 - Elsevier
Many industries are striving for the development of more reliable and robust β-galactosidase
biosensors that exhibit high response rate, increased detection limit and enriched useful …

Minimizing inclusion body formation during recombinant protein production in Escherichia coli at bench and pilot plant scale

F Hoffmann, J van den Heuvel, N Zidek… - Enzyme and microbial …, 2004 - Elsevier
Many recombinant proteins partially aggregate into inclusion bodies during production in
Escherichia coli in batch culture on defined medium. Production on complex medium …

Switchable reporter enzymes based on mutually exclusive domain interactions allow antibody detection directly in solution

S Banala, SJA Aper, W Schalk, M Merkx - ACS chemical biology, 2013 - ACS Publications
Detection of antibodies is essential for the diagnosis of many diseases including infections,
allergies, and autoimmune diseases. Current heterogeneous immunoassays require …

[HTML][HTML] Early detection of cancer: Focus on antibody coated metal and magnetic nanoparticle-based biosensors

G Ghosh - Sensors International, 2020 - Elsevier
Cancer is a highly fatal disease, and due to contemporary lifestyle and growing,
environmental pollution chances of cancer are increasing, which is a global threat. The high …

Antigen peptide-based immunosensors for rapid detection of antibodies and antigens

L Tian, T Heyduk - Analytical chemistry, 2009 - ACS Publications
The homogeneous immunosensor design described here utilizes the bivalent nature of the
antibody. Antigen peptide is conjugated using flexible linkers with short complementary …

Construction and potential applications of biosensors for proteins in clinical laboratory diagnosis

X Liu, H Jiang - Sensors, 2017 - mdpi.com
Biosensors for proteins have shown attractive advantages compared to traditional
techniques in clinical laboratory diagnosis. In virtue of modern fabrication modes and …

Engineering allosteric regulation into biological catalysts

J Fastrez - ChemBioChem, 2009 - Wiley Online Library
Enzymes and ribozymes constitute two classes of biological catalysts. The activity of many
natural enzymes is regulated by the binding of ligands that have different structures than …