Lobular neoplasia (LN) is an atypical proliferation of small, dyscohesive epithelial cells
within the terminal duct lobular unit (TDLU), with or without pagetoid extension and …

This review reflects a collaboration between the American Registry of Pathology (the
publisher of the Armed Forces Institute of Pathology Fascicles) and Annals of Diagnostic …

Atypical hyperplasia and lobular carcinoma in situ are rare proliferative breast lesions,
growing inside ducts and terminal ducto-lobular units. They represent a marker of increased …

Management of classic lobular neoplasia (cLN) diagnosed on core needle biopsy (CNB) is
controversial. Our aim in this study was to review cases of cLN diagnosed on CNB to …

Breast pathology is filled with pitfalls, including underdiagnosis of bland-appearing lesions,
both invasive and non-invasive, misdiagnosis of malignant lesions as belonging to the …

Purpose Classical type of lobular neoplasia (LN) spans a spectrum of disease, including
atypical lobular hyperplasia (ALH) and lobular carcinoma in situ (LCIS), classical lobular …

In 2018, it is estimated that over a quarter of a million new cases of invasive breast cancer
will be diagnosed in the United States (USA). Early detection and targeted therapies have …

Results: Median age of patients (mean±SD, range) was 56 years (56.6±9.7, 36–74), while
median size of LCIS was 15 mm (15.3±5.9, 6–28). Final examination demonstrated IBC foci …

Background Lobular carcinoma in situ (LCIS) is a noninvasive neoplasm that is known to
have an increased relative risk for developing subsequent invasive breast carcinoma. Pure …

Introduction: Breast cancer is a heterogeneous disease, at morphological, molecular, and
clinical levels and this has significant implications for the diagnosis and management of the …