High blood pressure is reported in over two-thirds of patients with type 2 diabetes, and its
development coincides with the development of hyperglycaemia. Many pathophysiological …

Diabetes mellitus is a disease of metabolic dysregulation, most notably abnormal glucose
metabolism, accompanied by characteristic long-term complications. The complications that …

Albuminuria in Type 1 (insulin-dependent) diabetes is not only an indication of renal
disease, but a new, independent risk-marker of proliferative retinopathy and …

Glucose toxicity is a well-established entity that has been shown in animal models of
diabetes to contribute to development of insulin resistance and impaired insulin secretion. In …

Background Patients with type 1 diabetes mellitus and microalbuminuria often have
elevated blood pressure while they are asleep, but it is not known whether the elevation …

Advances in cardiovascular research during the past two decades have resulted in an
improved understanding of the chain of events that lead to end-stage coronary artery …

The prevalence of and interrelationships among all four major complications of insulin-
dependent diabetes mellitus (IDDM) and their risk factors are being examined in a large …

The relation between urinary albumin excretion rate (AER) and vascular disease was
studied in 187 subjects aged over 40 selected from 1084 cases attending a diabetic …

Background The high relative mortality among patients with insulin-dependent diabetes
mellitus results mainly from diabetic nephropathy. The cumulative incidence of nephropathy …

The hearts obtained at autopsy of 67 patients with hypertension, diabetes mellitus, or both
were examined microscopically and histochemically, and the amount of fibrosis was …