Osteocytes play a critical role in maintaining bone homeostasis and in regulating skeletal
response to hormones and mechanical loading. Substantial evidence have demonstrated …

Osteoporosis care has evolved markedly over the last 50 years, such that there are now an
established clinical definition, validated methods of fracture risk assessment and a range of …

Systematic bone loss is commonly complicated with inflammatory bowel diseases (IBDs)
with unclear pathogenesis and uncertain treatment. In experimental colitis mouse models …

Osteoporosis is the most common degenerative orthopedic disease in the elderly. Recently,
the therapeutic methods for osteoporosis have shifted towards the regulation of local …

Osteoporosis (OP) is a chronic bone disease characterized by aberrant microstructure and
macrostructure of bone, leading to reduced bone mass and increased risk of fragile …

Osteoporosis is a common disease that affects millions of patients worldwide and is most
common in menopausal women. The main characteristics of osteoporosis are low bone …

Osteoporosis is the most common metabolic skeletal disease. It is characterized by the
deterioration of the skeletal microarchitecture and bone loss, leading to ostealgia, and even …

Osteoporosis is a systemic metabolic bone disease characterized by the descending bone
mass and destruction of bone microstructure, which tends to result in the increased bone …

Imbalances in bone formation and resorption cause osteoporosis. Mounting evidence
supports that brain-derived neurotrophic factor (BDNF) implicates in this process. 7, 8 …

Gut microbiota is key to human health and disease. Convincing studies have demonstrated
that dysbiosis in the commensal gut microbiota is associated with intestinal and extra …