Background: Epidermal growth factor receptor-tyrosine kinase (EGFR-TK) is a well-known
hallmark of oral and oropharyngeal cancers, as its overexpression leads to poor prognosis …

Aim: Using molecular hybridization approach, novel 18 quinoline derivatives (6a–11) were
designed and synthesized as EGFR-TK inhibitors. Materials & methods: The antiproliferative …

The heterocyclic compounds have a great significance in medicinal chemistry because they
have extensive biological activities. Cancer is globally the leading cause of death and it is a …

Epidermal growth factor receptor (EGFR) is a promising target for the treatment of different
types of malignant tumors. Therefore, a combined molecular modeling study was performed …

On the one hand, to obtain a novel next-generation anticancer metal agent; on the other
hand, to improve the targeting ability and decrease side effects of metal agent, we proposed …

Abstract Epidermal Growth Factor Receptor is a multifunctional receptor and is an important
member of tyrosine kinase family. Investigation on mechanism of tumour progression and its …

Background: Epidermal Growth Factor Receptor (EGFR) and members of its homologous
protein family mediate transmembrane signal transduction by binding to a specific ligand …

Benzothiazoles are a class of heterocycles with multiple applications as anticancer,
antibiotic, antiviral, and anti‐inflammatory agents. Benzothiazole is a privileged scaffold in …

We report the synthesis, spectroscopic characterization, molecular docking and biological
evaluation of nine pyrazino‐imidazolinone derivatives. These derivatives were evaluated for …

Ethanol extracts of Caulerpa racemose (Forsskål) J. Agardh, 1873, Dictyopteris
acrostichoides (J. Agardh) Bornet, 1885, Halimeda opuntia (Linnaeus) JV Lamouroux, 1816 …