Thoracic aortic aneurysms involving the root and/or the ascending aorta enlarge over time
until an acute tear in the intimal layer leads to a highly fatal condition, an acute aortic …

Abstract Aim The “2022 ACC/AHA Guideline for the Diagnosis and Management of Aortic
Disease” provides recommendations to guide clinicians in the diagnosis, genetic evaluation …

Inherited thoracic aortopathies denote a group of congenital conditions that predispose to
disease of the thoracic aorta. Aortic wall weakness and abnormal aortic hemodynamic …

Acute aortic syndromes comprise a group of potentially fatal conditions that result from
weakening of the aortic vessel wall. Pre-emptive surgical intervention is currently reserved …

Background: Mural cells in ascending aortic aneurysms undergo phenotypic changes that
promote extracellular matrix destruction and structural weakening. To explore this biology …

The bicuspid aortic valve, a kind of heart disease that comes from parents, has been paid
attention around the world. Although most bicuspid aortic valve (BAV) patients will suffer …

Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …

Importance The risk of adverse events from ascending thoracic aorta aneurysm (TAA) is
poorly understood but drives clinical decision-making. Objective To evaluate the association …

Bicuspid aortic valve disease is a common congenital cardiac disorder, being present in 1%
to 2% of the general population. Associated aortopathy is a common finding in patients with …

Importance The natural history of ascending aortic aneurysm (AsAA) is currently not well
characterized. Objective To summarize and analyze existing literature on the natural history …