Molecular approaches to determine the multiplicity of Plasmodium infections

D Zhong, C Koepfli, L Cui, G Yan - Malaria journal, 2018 - Springer
Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

Diversity and Multiplicity of P. falciparum infections among asymptomatic school children in Mbita, Western Kenya

AO Touray, VA Mobegi, F Wamunyokoli, JK Herren - Scientific reports, 2020 - nature.com
Multiplicity of infection (MOI) and genetic diversity of P. falciparum infections are important
surrogate indicators for assessing malaria transmission intensity in different regions of …

The Diversity, Multiplicity of Infection and Population Structure of P. falciparum Parasites Circulating in Asymptomatic Carriers Living in High and Low Malaria …

Z Abukari, R Okonu, SB Nyarko, AC Lo, CC Dieng… - Genes, 2019 - mdpi.com
Background: Diversity in Plasmodium falciparum poses a major threat to malaria control and
elimination interventions. This study utilized 12 polymorphic microsatellite (MS) markers and …

Multiplicity of Infection and Disease Severity in Plasmodium vivax

MA Pacheco, M Lopez-Perez, AF Vallejo… - PLoS neglected …, 2016 - journals.plos.org
Background Multiplicity of infection (MOI) refers to the average number of distinct parasite
genotypes concurrently infecting a patient. Although several studies have reported on MOI …

Multiplicity and molecular epidemiology of Plasmodium vivax and Plasmodium falciparum infections in East Africa

D Zhong, E Lo, X Wang, D Yewhalaw, G Zhou… - Malaria journal, 2018 - Springer
Background Parasite genetic diversity and multiplicity of infection (MOI) affect clinical
outcomes, response to drug treatment and naturally-acquired or vaccine-induced immunity …

Genetic Polymorphism of msp1 and msp2 in Plasmodium falciparum Isolates from Côte d'Ivoire versus Gabon

W Yavo, A Konaté, DP Mawili-Mboumba… - Journal of …, 2016 - Wiley Online Library
Introduction. The characterization of genetic profile of Plasmodium isolates from different
areas could help in better strategies for malaria elimination. This study aimed to compare P …

Beyond the entomological inoculation rate: characterizing multiple blood feeding behavior and Plasmodium falciparum multiplicity of infection in Anopheles …

S Das, M Muleba, JC Stevenson, JC Pringle… - Parasites & vectors, 2017 - Springer
Background A commonly used measure of malaria transmission intensity is the
entomological inoculation rate (EIR), defined as the product of the human biting rate (HBR) …

Confirmation of the absence of local transmission and geographic assignment of imported falciparum malaria cases to China using microsatellite panel

Y Liu, SK Tessema, M Murphy, S Xu, A Schwartz… - Malaria journal, 2020 - Springer
Background Current methods to classify local and imported malaria infections depend
primarily on patient travel history, which can have limited accuracy. Genotyping has been …

Genetic polymorphism of Merozoite Surface Protein-2 (MSP-2) in Plasmodium falciparum isolates from Pawe District, North West Ethiopia

H Mohammed, M Kassa, A Assefa, M Tadesse… - PLoS …, 2017 - journals.plos.org
Background In malaria endemic regions, Plasmodium falciparum infection is characterized
by extensive genetic diversity. Describing this diversity provides important information about …

P. falciparum msp1 and msp2 genetic diversity in P. falciparum single and mixed infection with P. malariae among the asymptomatic population in Southern Benin

R Agonhossou, R Akoton, H Lagnika, OY Djihinto… - Parasitology …, 2022 - Elsevier
Plasmodium falciparum and Plasmodium malariae infections are prevalent in malaria-
endemic countries. However, very little is known about their interactions especially the effect …