Yersinia

JM Petersen, LM Gladney… - Manual of clinical …, 2015 - Wiley Online Library
The pathogenic Yersinia species, Y. pseudotuberculosis, Y. enterocolitica, and Y. pestis, are
zoonotic agents that cause disease in humans. Human clinical infections caused by Y …

Development of a pair of real-time loop mediated isothermal amplification assays for detection of Yersinia pestis, the causative agent of plague

R Singh, V Pal, NK Tripathi, AK Goel - Molecular and Cellular Probes, 2020 - Elsevier
Yersinia pestis, the causative agent of plague mainly infects rodents, while humans are the
accidental host. The conventional diagnostic methods available for Y. pestis exhibit cross …

Immunisation of two rodent species with new live-attenuated mutants of Yersinia pestis CO92 induces protective long-term humoral-and cell-mediated immunity …

BL Tiner, J Sha, Y Cong, ML Kirtley, JA Andersson… - npj Vaccines, 2016 - nature.com
We showed recently that the live-attenuated Δlpp ΔmsbB Δail and Δlpp ΔmsbB:: ailL2
mutants of Yersinia pestis CO92 provided short-term protection to mice against developing …

[HTML][HTML] Expression, refolding, and initial structural characterization of the Y. pestis Ail outer membrane protein in lipids

LA Plesniak, R Mahalakshmi, C Rypien, Y Yang… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Ail is an outer membrane protein and virulence factor of Yersinia pestis, an extremely
pathogenic, category A biothreat agent, responsible for precipitating massive human plague …

A mutant with aberrant extracellular LcrV-YscF interactions fails to form pores and translocate Yop effector proteins but retains the ability to trigger Yop secretion in …

DE Harmon, JL Murphy, AJ Davis… - Journal of …, 2013 - Am Soc Microbiol
The plasmid-encoded type three secretion system (TTSS) of Yersinia spp. is responsible for
the delivery of effector proteins into cells of the innate immune system, where these effectors …

[HTML][HTML] Proteolysis of plasminogen activator inhibitor‐1 by Yersinia pestis remodulates the host environment to promote virulence

JL Eddy, JA Schroeder, DL Zimbler, AJ Caulfield… - Journal of Thrombosis …, 2016 - Elsevier
Essentials• Effect of plasminogen activator inhibitor (PAI)‐1 on plague and its Y. pestis
cleavage is unknown.• An intranasal mouse model of infection was used to determine the …

Rapid Focused Sequencing: A Multiplexed Assay for Simultaneous Detection and Strain Typing of Bacillus anthracis, Francisella tularensis, and Yersinia pestis

RS Turingan, HU Thomann, A Zolotova, E Tan… - PLoS …, 2013 - journals.plos.org
Background The intentional release of Bacillus anthracis in the United States in 2001 has
heightened concern about the use of pathogenic microorganisms in bioterrorism attacks …

Deletion of Braun lipoprotein gene (lpp) attenuates Yersinia pestis KIM/D27 strain: role of Lpp in modulating host immune response, NF-κB activation and cell death

T Liu, SL Agar, J Sha, AK Chopra - Microbial pathogenesis, 2010 - Elsevier
The pathogenic species of yersiniae potently blocks immune responses in host cells by
using the type III secretion apparatus and its effector proteins. In this study, we characterized …

Yersinia

ME Schriefer, JM Petersen - Manual of clinical microbiology, 2011 - Wiley Online Library
The pathogenic Yersinia species, Y. pseudotuberculosis, Y. enterocolitica, and Y. pestis, are
zoonotic agents that cause disease in humans ranging from mild gastroenteritis to life …

Cluster analysis of host cytokine responses to biodefense pathogens in a whole blood ex vivo exposure model (WEEM)

BA Chromy, IK Fodor, NK Montgomery, PA Luciw… - BMC microbiology, 2012 - Springer
Background Rapid detection and therapeutic intervention for infectious and emerging
diseases is a major scientific goal in biodefense and public health. Toward this end, cytokine …