Objective Enlarged vestibular aqueduct is the most common radiographically identified
cause of congenital sensorineural hearing loss and is frequently progressive. Imaging is …

The estimated prevalence of permanent bilateral hearing loss (HL) in children is 1.33 per
1000 live births, increasing to 3.5 per 1000 adolescents, presumably reflecting additional …

Abstract Objectives/Hypothesis: Identify correlations among SLC26A4 genotype, cochlear
structural anomalies, and hearing loss associated with enlargement of the vestibular …

Objective Enlarged vestibular aqueduct (EVA) is the most common inner ear malformation.
While a strong correlative relationship between EVA and hearing loss is well established, its …

Objective: To describe the results of a thorough evaluation in a large series of patients with
an enlarged vestibular aqueduct (EVA), focusing on vestibular manifestations with …

Objective Enlarged vestibular aqueduct (EVA) is a congenital condition that can lead to
various outcomes in pediatric patients including hearing loss and vestibular dysfunction. Our …

Recessive mutations in the SLC26A4 gene are a common cause of hereditary hearing
impairment worldwide. Previous studies have demonstrated that different SLC26A4 …

The human gene SLC26A4 and the mouse ortholog Slc26a4 code for the protein pendrin,
which is an anion exchanger expressed in apical membranes of selected epithelia. In the …

OBJECTIVE: The objective of this study is to describe the vestibular symptoms in pediatric
patients with enlarged vestibular aqueduct (EVA) anomaly. METHODS: Retrospective chart …

Conclusions. The present study confirmed the clinical characteristics of patients with
SLC26A4 mutations: congenital, fluctuating, and progressive hearing loss usually …