Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance
Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …
Overcoming the blood–brain barrier for the therapy of malignant brain tumor: Current status and prospects of drug delivery approaches
K Mitusova, OO Peltek, TE Karpov… - Journal of …, 2022 - Springer
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …
therapy, currently, there is no significant progress in the treatment of different types of brain …
Engineering macrophage exosome disguised biodegradable nanoplatform for enhanced sonodynamic therapy of glioblastoma
Sonodynamic therapy (SDT) exhibits high tissue penetration and negligible radiation
damage to normal tissues, and thus emerges as a promising cancer therapeutic modality for …
damage to normal tissues, and thus emerges as a promising cancer therapeutic modality for …
[HTML][HTML] The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy
Following its discovery more than 30 years ago, the enhanced permeability and retention
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …
Brain co‐delivery of temozolomide and cisplatin for combinatorial glioblastoma chemotherapy
Glioblastoma (GBM) is an intractable malignancy with high recurrence and mortality.
Combinatorial therapy based on temozolomide (TMZ) and cisplatin (CDDP) shows …
Combinatorial therapy based on temozolomide (TMZ) and cisplatin (CDDP) shows …
Organic semiconducting macromolecular dyes for NIR‐II photoacoustic imaging and photothermal therapy
C Yin, X Li, Y Wang, Y Liang, S Zhou… - Advanced Functional …, 2021 - Wiley Online Library
Owing to the unique advantages of photoacoustic imaging (PAI) and photothermal therapy
(PTT) conducted over the near‐infrared‐II (NIR‐II) window, the development of high …
(PTT) conducted over the near‐infrared‐II (NIR‐II) window, the development of high …
Brain co‐delivery of first‐line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy
Glioblastoma (GBM) is a central nervous system tumor with poor prognosis due to the rapid
development of resistance to mono chemotherapy and poor brain targeted delivery …
development of resistance to mono chemotherapy and poor brain targeted delivery …
An optimized ionizable cationic lipid for brain tumor-targeted siRNA delivery and glioblastoma immunotherapy
S Liu, J Liu, H Li, K Mao, H Wang, X Meng, J Wang… - Biomaterials, 2022 - Elsevier
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor
with a high mortality rate. Immunotherapy has achieved promising clinical results in multiple …
with a high mortality rate. Immunotherapy has achieved promising clinical results in multiple …
Overview of current drug delivery methods across the blood–brain barrier for the treatment of primary brain tumors
R Haumann, JC Videira, GJL Kaspers… - CNS drugs, 2020 - Springer
Existing drug delivery methods have not led to a significant increase in survival for patients
with malignant primary brain tumors. While the combination of conventional therapies …
with malignant primary brain tumors. While the combination of conventional therapies …
Mechanisms of resistance and current treatment options for glioblastoma multiforme (GBM)
Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …