A review of effects of atorvastatin in cancer therapy

Z Shaghaghi, M Alvandi, S Farzipour, MR Dehbanpour… - Medical oncology, 2022 - Springer
Cancer is one of the most challenging diseases to manage. A sizeable number of
researches are done each year to find better diagnostic and therapeutic strategies. At the …

Atorvastatin Induces Mitochondria-Dependent Ferroptosis via the Modulation of Nrf2-xCT/GPx4 Axis

Q Zhang, H Qu, Y Chen, X Luo, C Chen… - Frontiers in Cell and …, 2022 - frontiersin.org
As one of the cornerstones of clinical cardiovascular disease treatment, statins have an
extensive range of applications. However, statins commonly used have side reactions …

Targeting cellular metabolism in head and neck cancer precision medicine era: A promising strategy to overcome therapy resistance

X Lin, W Zhou, Z Liu, W Cao, C Lin - Oral Diseases, 2023 - Wiley Online Library
Head and neck squamous cell carcinoma (HNSCC) is among the most prevalent cancer
worldwide, with the most severe impact on quality of life of patients. Despite the …

Engineered microencapsulated lactoferrin nanoconjugates for oral targeted treatment of colon cancer

YM Elmorshedy, M Teleb, MA Sallam… - …, 2023 - ACS Publications
Despite current progress in the development of targeted therapies for cancer treatment,
there is a lack in convenient therapeutics for colorectal cancer (CRC). Lactoferrin …

Countermeasure development against space radiation-induced gastrointestinal carcinogenesis: Current and future perspectives

S Suman, AJ Fornace Jr - Life Sciences in Space Research, 2022 - Elsevier
A significantly higher probability of space radiation-induced gastrointestinal (GI) cancer
incidence and mortality after a Mars mission has been projected using biophysical and …

Repurposing of atorvastatin and metformin denotes their individual and combined antiproliferative effects in non‐small cell lung cancer

EI Salim, S Elsebakhy… - Fundamental & Clinical …, 2024 - Wiley Online Library
Background Due to the limited success in the treatment of lung adenocarcinomas, new
treatment protocols are urgently needed to increase the curability rate and the survival of …

Expression of Prostaglandin Genes and β-Catenin in Whole Blood as Potential Markers of Muscle Degeneration

A Wajda, D Bogucka, B Stypińska… - International Journal of …, 2023 - mdpi.com
Prostaglandin signaling pathways are closely related to inflammation, but also muscle
regeneration and processes associated with frailty and sarcopenia, whereas β-catenin …

Small molecule inhibitors for cancer metabolism: promising prospects to be explored

D Liu, HP Wang, XX Li, JF Liu, YL Zhang… - Journal of Cancer …, 2023 - Springer
Background Abnormal metabolism is the main hallmark of cancer, and cancer metabolism
plays an important role in tumorigenesis, metastasis, and drug resistance. Therefore …

Proteomic detection of COX-2 pathway-related factors in patients with adenomyosis

J Zhang, L Shi, J Duan, M Li, C Li - PeerJ, 2024 - peerj.com
Background Investigating the relationship between cyclooxygenase-2 (COX-2) pathway-
related factors and clinical features in patients with adenomyosis by proteomics could …

Effectiveness of Plant Bioactive Compounds as Colorectal Cancer Cell Line Inhibitors: A Systematic Review

A Rahmi, AT Rahman, N Annisa… - Jurnal Biologi …, 2023 - jurnalfkip.unram.ac.id
Cancer is a non-communicable disease and one of the highest causes of human death. It
has been well documented that active substances have been shown in vitro to have …