Cholestasis is associated with systemic accumulation of bile salts and with deficiency of bile
in the intestinal lumen. During the past years bile salts have been identified as signaling …

Objective: To investigate the effects of raw rhubarb (RR) on the intestinal barrier dysfunction
and endotoxemia in rat models with obstructive jaundice (OJ). Methods: Twenty-seven …

Bile acids are oxidized sterols derived from cholesterol that result from a host of enzymatic
reactions that take place in hepatocytes. These enzymatic pathways are classified into the …

Our group and others have previously shown that genistein combined polysaccharide
(GCP), an aglycone isoflavone-rich extract with high bioavailability and low toxicity, can …

Mechanisms by which hydrophobic bile salts cause tissue changes below their critical
micellar concentration (CMC, 1–2mM) and above (4–8mM) remain poorly understood. In this …

Background: Intestinal disorders, including infectious diseases (ID), inflammatory bowel
disease (IBD) and irritable bowel syndrome (IBS), are common in the European population …

As an endogenous anti-damage material in organism, Taurine (Tau) stems from food and
almost resides in all animals' cells by means of liberation, which could be found in diverse …

The effect of ursodeoxycholic acid and piperacillin-tazobactam on acute renal failure
associated with obstructive jaundice Objective: Acute renal failure associated with …

Cholestatische leverziekten worden gekarakteriseerd door verminderd galtransport van de
lever naar het darmlumen. Fysiologische gevolgen hiervan zijn de accumulatie van …

METHODS Cell culture. All cells were maintained using standard culture techniques in a
humidified 37 C, 5% CO2 incubator. The human, telomerase-immortalized, Barrett's-derived …