The pathogenesis of rheumatoid arthritis
S Alivernini, GS Firestein, IB McInnes - Immunity, 2022 - cell.com
Significant recent progress in understanding rheumatoid arthritis (RA) pathogenesis has led
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …
to improved treatment and quality of life. The introduction of targeted-biologic and-synthetic …
Oral microbiota in human systematic diseases
Oral bacteria directly affect the disease status of dental caries and periodontal diseases. The
dynamic oral microbiota cooperates with the host to reflect the information and status of …
dynamic oral microbiota cooperates with the host to reflect the information and status of …
Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities
G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
associated with other chronic inflammation-driven disorders, including cardio-metabolic …
Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications
G Hajishengallis - Periodontology 2000, 2022 - Wiley Online Library
Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …
[HTML][HTML] Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities
Bone marrow (BM)-mediated trained innate immunity (TII) is a state of heightened immune
responsiveness of hematopoietic stem and progenitor cells (HSPC) and their myeloid …
responsiveness of hematopoietic stem and progenitor cells (HSPC) and their myeloid …
The gut–joint axis in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder that primarily
affects the joints. One hypothesis for the pathogenesis of RA is that disease begins at …
affects the joints. One hypothesis for the pathogenesis of RA is that disease begins at …
The oral microbiota: dynamic communities and host interactions
RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis
Neutrophil infiltration is a hallmark of periodontitis, a prevalent oral inflammatory condition in
which Th17-driven mucosal inflammation leads to destruction of tooth-supporting bone …
which Th17-driven mucosal inflammation leads to destruction of tooth-supporting bone …
The continuum of aging and age-related diseases: common mechanisms but different rates
Geroscience, the new interdisciplinary field that aims to understand the relationship between
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …
aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on …
The structure of dental plaque microbial communities in the transition from health to dental caries and periodontal disease
AM Valm - Journal of molecular biology, 2019 - Elsevier
The human oral cavity harbors diverse communities of microbes that live as biofilms: highly
ordered, surface-associated assemblages of microbes embedded in an extracellular matrix …
ordered, surface-associated assemblages of microbes embedded in an extracellular matrix …