Squamous cell carcinoma (SCC) is an epithelial malignancy involving many anatomical
sites and is the most common cancer capable of metastatic spread. Development of early …

Over 90% of all cancers are carcinomas, malignancies derived from cells of epithelial origin.
As carcinomas progress, these tumors may lose epithelial morphology and acquire …

The epidermal growth factor receptor (EGFR) is one of most potent oncogenes that are
commonly altered in cancers. As a receptor tyrosine kinase, EGFR's kinase activity has been …

Purpose: Our study aimed to investigate whether CAF (cancer-associated fibroblasts) were
involved in long noncoding RNAs (lncRNA)-regulated radioresponse in esophageal …

In the current study, new benzimidazole-based 1, 3, 4-oxadiazole derivatives have been
synthesized and characterized by NMR, IR, MS, and elemental analysis. The final …

One of the mechanisms of the antitumor activity of green tea (−)‐epigallocatechin‐3‐gallate
(EGCG) is associated with its effect on epidermal growth factor receptor (EGFR)‐mediated …

Redox regulation of epidermal growth factor receptor (EGFR) signaling helps protect cells
against oxidative stress. In this study, we investigated whether the cytotoxicity of an EGFR …

Epidermal growth factor receptor (EGFR) is one of the most common amplified and
overexpressed oncogenes in esophageal squamous cell carcinoma (ESCC), while the …

Esophageal squamous cell carcinoma (ESCC) is the predominant histological subtype of
esophageal cancer in Asia, characterized by high incidence and mortality rate. Although …

Receptor tyrosine kinases (RTKs) are in the focus of targeted therapy for epithelial tumors.
Our study addressed the role of EGFR, HER2 and HER3 expression and dimerization in …