The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

Mitochondria are known to generate approximately 90% of cellular reactive oxygen species
(ROS). The imbalance between mitochondrial reactive oxygen species (mtROS) production …

Pyroptosis, a type of Gasdermin-mediated cell death, contributes to an exacerbation of
inflammation. To test the hypothesis that GSDME-mediated pyroptosis aggravates the …

Extracellular vesicles (EVs) have unique structural, compositional, and morphological
characteristics as well as predominant physiochemical stability and biocompatibility …

Inflammation is an important driver of atherosclerosis, the underlying pathology of
cardiovascular diseases. Therefore, therapeutic targeting of inflammatory pathways is …

Cardiovascular disease is the leading cause of death worldwide, both in the general
population and among patients with chronic kidney disease (CKD). In most cases, the …

INTRODUCTION Canonical inflammasomes are multicomponent protein complexes that
play key roles in immune surveillance of infections and danger by activating caspase-1 …

Background—Altered composition of the gut microbiota is involved in both the onset and
progression of obesity and diabetes mellitus. However, the link between gut microbiota and …

Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …

Atherosclerosis is the disease process that underlies heart attack and stroke. Advanced
lesions at risk of rupture are characterized by the pathological accumulation of diseased …