MicroRNA-155 deficiency leads to decreased atherosclerosis, increased white adipose tissue obesity, and non-alcoholic fatty liver disease: a novel mouse model of …

A Virtue, C Johnson, J Lopez-Pastraña, Y Shao… - Journal of Biological …, 2017 - ASBMB
Obesity paradox (OP) describes a widely observed clinical finding of improved
cardiovascular fitness and survival in some overweight or obese patients. The molecular …

Anti-inflammatory actions of soluble Ninjurin-1 ameliorate atherosclerosis

S Jeon, TK Kim, SJ Jeong, IH Jung, N Kim, MN Lee… - Circulation, 2020 - Am Heart Assoc
Background: Macrophages produce many inflammation-associated molecules, released by
matrix metalloproteinases, such as adhesion molecules, and cytokines, as well, which play a …

Novel iron oxide–cerium oxide core–shell nanoparticles as a potential theranostic material for ROS related inflammatory diseases

Y Wu, Y Yang, W Zhao, ZP Xu, PJ Little… - Journal of Materials …, 2018 - pubs.rsc.org
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are key signaling
molecules that play an important role in the inflammation and progression of many diseases …

The anti-inflammatory effects of formononetin and ononin on lipopolysaccharide-induced zebrafish models based on lipidomics and targeted transcriptomics

L Luo, J Zhou, H Zhao, M Fan, W Gao - Metabolomics, 2019 - Springer
Introduction Formononetin (MBHS) and its glycosylated derivative ononin (MBHG), as the
major isoflavones, have exhibited the anti-inflammatory impacts on the lipopolysaccharide …

Lysophospholipids induce innate immune transdifferentiation of endothelial cells, resulting in prolonged endothelial activation

X Li, L Wang, P Fang, Y Sun, X Jiang, H Wang… - Journal of Biological …, 2018 - ASBMB
Innate immune cells express danger-associated molecular pattern (DAMP) receptors, T-cell
costimulation/coinhibition receptors, and major histocompatibility complex II (MHC-II). We …

Enhancement of functionality and therapeutic efficacy of cell-based therapy using mesenchymal stem cells for cardiovascular disease

CW Yun, SH Lee - International journal of molecular sciences, 2019 - mdpi.com
Cardiovascular disease usually triggers coronary heart disease, stroke, and ischemic
diseases, thus promoting the development of functional failure. Mesenchymal stem cells …

Advances in Atherosclerosis Theranostics Harnessing Iron Oxide‐Based Nanoparticles

S Wang, H He, Y Mao, Y Zhang, N Gu - Advanced Science, 2024 - Wiley Online Library
Atherosclerosis, a multifaceted chronic inflammatory disease, has a profound impact on
cardiovascular health. However, the critical limitations of atherosclerosis management …

Association between changes in coronary artery disease progression and treatment with biologic agents for severe psoriasis

KF Hjuler, M Bøttcher, C Vestergaard… - JAMA …, 2016 - jamanetwork.com
Importance Inflammatory pathways of psoriasis share similarities with the mechanisms
identified in atherosclerosis, and the association between psoriasis and cardiovascular …

Targeted delivery of platelet membrane modified extracellular vesicles into atherosclerotic plaque to regress atherosclerosis

Q Li, Z Huang, Z Pang, Q Wang, J Gao, J Chen… - Chemical Engineering …, 2023 - Elsevier
Atherosclerosis is a major underlying cause of cardiovascular disease. Although certain
success has been achieved in treatment for atherosclerosis, the risk of cardiovascular …

Glucagon-like peptide-1 receptor agonist dulaglutide prevents ox-LDL-induced adhesion of monocytes to human endothelial cells: An implication in the treatment of …

W Chang, F Zhu, H Zheng, Z Zhou, P Miao, L Zhao… - Molecular …, 2019 - Elsevier
Atherosclerosis is a common comorbidity of type II diabetes and a leading cause of death
worldwide. The presence of oxidized low-density lipoprotein (ox-LDL) drives atherogenesis …