Chronotherapeutics aim at treating illnesses according to the endogenous biologic rhythms,
which moderate xenobiotic metabolism and cellular drug response. The molecular clocks …

Despite significant advances in oncological research, cancer nowadays remains one of the
main causes of mortality and morbidity worldwide. New treatment techniques, as a rule …

Background Drug-induced drug resistance in cancer has been attributed to diverse
biological mechanisms at the individual cell or cell population scale, relying on …

Background A thorough understanding of the ecological and evolutionary mechanisms that
drive the phenotypic evolution of neoplastic cells is a timely and key challenge for the cancer …

The present paper focuses on the development of a population balance model (PBM)
accounting for microbial population dynamics in a fluctuating environment. Heterogeneity …

For population systems modeled by age‐structured hyperbolic partial differential equations
(PDEs), we redesign the existing feedback laws, designed under the assumption that the …

In this paper, we perform a mathematical analysis of our proposed nonlinear, multiscale
mathematical model of physiologically structured quiescent and proliferating cell …

Stability analysis of an autonomous epidemic model of an age-structured sub-populations of
susceptible, infected, precancerous and cancer cells and unstructured sub-population of …

In this paper we study the nonlinear age-structured model of a polycyclic two-phase
population dynamics including delayed effect of population density growth on the mortality …

This article reviews the current knowledge and recent advancements in computational
modeling of the cell cycle. It offers a comparative analysis of various modeling paradigms …