Genomics of disease risk in globally diverse populations
Risk of disease is multifactorial and can be shaped by socio-economic, demographic,
cultural, environmental and genetic factors. Our understanding of the genetic determinants …
cultural, environmental and genetic factors. Our understanding of the genetic determinants …
Polygenic scores in cancer
Since the publication of the first genome-wide association study for cancer in 2007,
thousands of common alleles that are associated with the risk of cancer have been …
thousands of common alleles that are associated with the risk of cancer have been …
[HTML][HTML] Carcinogenicity assessment: Addressing the challenges of cancer and chemicals in the environment
Cancer is a key public health concern, being the second leading cause of worldwide
morbidity and mortality after cardiovascular diseases. At the global level, cancer prevalence …
morbidity and mortality after cardiovascular diseases. At the global level, cancer prevalence …
[HTML][HTML] A comprehensive analysis of racial disparities in chemical biomarker concentrations in United States women, 1999–2014
VK Nguyen, A Kahana, J Heidt, K Polemi… - Environment …, 2020 - Elsevier
Background Stark racial disparities in disease incidence among American women remain a
persistent public health challenge. These disparities likely result from complex interactions …
persistent public health challenge. These disparities likely result from complex interactions …
[HTML][HTML] Clinical and molecular aspects of breast cancer: Targets and therapies
RLN Godone, GM Leitão, NB Araújo… - Biomedicine & …, 2018 - Elsevier
Breast Cancer is a complex disease characterized by the occurrence of multiple molecular
alterations. Currently, some molecular markers are in use for breast cancer diagnostic …
alterations. Currently, some molecular markers are in use for breast cancer diagnostic …
Living with metastatic cancer: a roadmap for future research
Simple Summary Although people with metastatic cancer are living longer with their
disease, they are faced with challenges that can interfere with their quality of life. These …
disease, they are faced with challenges that can interfere with their quality of life. These …
The contribution of genomic research to explaining racial disparities in cardiovascular disease: a systematic review
JS Kaufman, L Dolman, D Rushani… - American journal of …, 2015 - academic.oup.com
After nearly a decade of genome-wide association studies, no assessment has yet been
made of their contribution toward an explanation of the most prominent racial health …
made of their contribution toward an explanation of the most prominent racial health …
[HTML][HTML] Challenges of deciphering gastric cancer heterogeneity
P Hudler - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
Gastric cancer is in decline in most developed countries; however, it still accounts for a
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …
notable fraction of global mortality and morbidity related to cancer. High-throughput methods …
[HTML][HTML] Role of vitamin D in head and neck cancer—Immune function, anti-tumour effect, and its impact on patient prognosis
K Starska-Kowarska - Nutrients, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) describes a heterogeneous group of
human neoplasms of the head and neck with high rates of morbidity and mortality …
human neoplasms of the head and neck with high rates of morbidity and mortality …
[HTML][HTML] Histological classification, grading, staging, and prognostic indexing of female breast cancer in an African population: A 10-year retrospective study
WA Oluogun, KA Adedokun, MA Oyenike… - … journal of health …, 2019 - ncbi.nlm.nih.gov
Background: Breast cancer (BC) is a heterogeneous disease characterized with diverse
genetic and ethnic/racial variations that may influence tumor characteristics and prognosis …
genetic and ethnic/racial variations that may influence tumor characteristics and prognosis …