Rationale: Data suggest that altered antimicrobial concentrations are likely during
extracorporeal membrane oxygenation (ECMO). Objectives: The primary aim of this analysis …

Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on
individualized dosage optimization, integrating complex mathematical and statistical models …

The number of pharmacokinetic (PK) models of meropenem is increasing. However, the
daily role of these PK models in the clinic remains unclear, especially for critically ill patients …

Purpose This study aimed to investigate the pharmacokinetics and target attainment of
meropenem and compare the effect of meropenem dosing regimens in critically ill patients …

Extracorporeal membrane oxygenation (ECMO), as we all know, is a therapeutic modality
that provides life support for critically ill patients with severe respiratory or heart failure as an …

Objectives The purpose of this study was to develop a physiologically based
pharmacokinetic/pharmacodynamic model (PBPK/PD) of meropenem for critically ill …

Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on
individualized dosage optimization, integrating complex mathematical and statistical models …