Chronic liver diseases are often characterized by portal hy-pertension, an important
component of which is increased intrahepatic vascular resistance (IHVR). We have long …

Penile erection is dependent upon vascular smooth muscle relaxation in erectile tissue and
penile arteries, the principal mediator of relaxation being nitric oxide (NO). Evidence from …

5-Methyltetrahydrofolate (MTHF), the active form of folic acid, has been reported to restore
NO status in hypercholesterolemic patients. The mechanism of this effect remains to be …

Objective We tested the hypothesis that increased responsiveness of phospholipase D
(PLD) to angiotensin II (Ang II) is associated with increased oxidative stress and …

One of the current hypotheses on the pathophysiology of pre-eclampsia (PE) states that the
placenta secretes one or more cytotoxic factors resulting in maternal endothelial dysfunction …

Our previous work has revealed increased nitric oxide (NO) production in the cochlear
perilymph following noise stress. However, it is not clear if the increase of NO is related to …

We describe the synthesis and biological applications of a novel nitrogen‐15‐labeled
nitrone spin trap, 5‐ethoxycarbonyl‐5‐methyl‐1‐pyrroline N‐oxide ([15N] EMPO) for …

OBJECTIVES We investigated the development of nitrate tolerance after continuous
exposure to nitroglycerin (GTN) as compared with pentaerythritol tetranitrate (PETN) in …

Modulation of Ca 2+-activated K+ channel in renal artery endothelium in situ by nitric oxide
and reactive oxygen species. Background Endothelium-derived nitric oxide and reactive …

An NADPH oxidase is thought to be a main source of vascular superoxide (O2−) production.
The functional role of this oxidase, however, and the contribution of the different subunits of …