[HTML][HTML] Depression in patients with Parkinson's disease: current understanding of its neurobiology and implications for treatment
S Prange, H Klinger, C Laurencin, T Danaila… - Drugs & Aging, 2022 - Springer
Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …
The interplay between inflammation, oxidative stress, DNA damage, DNA repair and mitochondrial dysfunction in depression
P Czarny, P Wigner, P Galecki, T Sliwinski - Progress in Neuro …, 2018 - Elsevier
A growing body of evidence suggests that inflammation, mitochondrial dysfunction and
oxidant-antioxidant imbalance may play a significant role in the development and …
oxidant-antioxidant imbalance may play a significant role in the development and …
Depression in older adults
A Fiske, JL Wetherell, M Gatz - Annual review of clinical …, 2009 - annualreviews.org
Depression is less prevalent among older adults than among younger adults, but it can have
serious consequences. More than half of cases represent a first onset in later life. Although …
serious consequences. More than half of cases represent a first onset in later life. Although …
Parkinson's disease: clinical features and diagnosis
J Jankovic - Journal of neurology, neurosurgery & psychiatry, 2008 - jnnp.bmj.com
Objective: Parkinson's disease (PD) is a progressive neurological disorder characterised by
a large number of motor and non-motor features that can impact on function to a variable …
a large number of motor and non-motor features that can impact on function to a variable …
Depression and Parkinson's disease: current knowledge
L Marsh - Current neurology and neuroscience reports, 2013 - Springer
Depressive disturbances are common in patients with Parkinson's disease (PD) and
influence many other clinical aspects of the disease. In addition to causing inherent …
influence many other clinical aspects of the disease. In addition to causing inherent …
Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease
D Weintraub, T Simuni, C Caspell‐Garcia… - Movement …, 2015 - Wiley Online Library
This study was undertaken to determine the prevalence and correlates of cognitive
impairment (CI) and neuropsychiatric symptoms (NPS) in early, untreated patients with …
impairment (CI) and neuropsychiatric symptoms (NPS) in early, untreated patients with …
[HTML][HTML] Baicalein alleviates depression-like behavior in rotenone-induced Parkinson's disease model in mice through activating the BDNF/TrkB/CREB pathway
X Zhao, D Kong, Q Zhou, G Wei, J Song, Y Liang… - Biomedicine & …, 2021 - Elsevier
Background Parkinson's disease (PD) is the second most prevalent neurodegenerative
disorder in the world. In addition to motor symptoms, a variety of non-motor symptoms …
disorder in the world. In addition to motor symptoms, a variety of non-motor symptoms …
Current approaches to the treatment of Parkinson's disease
J Jankovic, LG Aguilar - Neuropsychiatric disease and treatment, 2008 - Taylor & Francis
Enormous progress has been made in the treatment of Parkinson's disease (PD). As a result
of advances in experimental therapeutics, many promising therapies for PD are emerging …
of advances in experimental therapeutics, many promising therapies for PD are emerging …
A controlled trial of antidepressants in patients with Parkinson disease and depression
Background: Parkinson disease (PD) is a common neurodegenerative disease affecting up
to 1 million individuals in the United States. Depression affects up to 50% of these patients …
to 1 million individuals in the United States. Depression affects up to 50% of these patients …
Telephone-based cognitive behavioral therapy for depression in Parkinson disease: a randomized controlled trial
Objective To determine whether, for patients with depression and Parkinson disease (PD),
telephone-based cognitive-behavioral treatment (T-CBT) alleviates depressive symptoms …
telephone-based cognitive-behavioral treatment (T-CBT) alleviates depressive symptoms …