Methods Human RA synovial fibroblasts were treated with concanavalin A (ConA), various
cytokines, and inhibitors of signal transduction molecules. The production of MIF by synovial …

AIM OF THE STUDY: Radix Toddaliae Asiaticae (RTA), also named “Sanbaibang”, is the dry
root bark of Toddalia asiatica (L.) Lam. and has long been used as a traditional ethnic …

Objectives. The overall non-response rate to biologics remains 30–40% for patients with RA
resistant to MTX. The objective of this study was to predict responsiveness to the anakinra …

The treatment of rheumatoid arthritis remains suboptimal; thus there is considerable interest
in the development of strategies that mediate tolerance to autoantigens. Using lentiviral …

Purpose The aim of this study is to investigate anti-arthritis activity using natural eggshell
membrane (NEM). Methods NEM was administered at 52 mg/kg, 200 mg/kg, and 400 mg/kg …

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. Genetic and
epidemiologic studies point to a relevant role of adaptive T-cell response interactions with …

Our previous studies demonstrated that oral administration of madecassoside could
markedly attenuate collagen-induced arthritis in rats, a rodent model of rheumatoid arthritis …

Fibrinogen is a provisional matrix protein of the coagulation system that following proteolytic
cleavage by the protease thrombin polymerizes to form fibrin, the structural basis of the …

Objective Infusion reaction is a major adverse event in patients with rheumatoid arthritis (RA)
treated with infliximab. The possible factors including Fcγ receptor (FcγR) polymorphism …

Psoriasis is a chronic inflammatory skin disease with a significant number of patients
suffering from additional joint involvement and other co-morbidities. The precise …