Plants are recognized as natural sources of antioxidants (eg, polyphenols, flavonoids,
vitamins, and other active compounds) that can be extracted by green solvents like water …

Methotrexate (MTX) is used as an anchor disease-modifying anti-rheumatic drugs
(DMARDs) in treating rheumatoid arthritis (RA) because of its potent efficacy and tolerability …

Methotrexate (MTX) is significantly more effective than and has a considerable advantage
over placebo in patients with severe and persistent rheumatoid arthritis (RA). The drug is …

Traditional Chinese medicine (TCM) is an important part of primary health care in Asian
countries that has utilized complex herbal formulations (consisting 2 or more medicinal …

Ageing, an unanswered question in the medical field, is a multifactorial process that results
in a progressive functional decline in cells, tissues and organisms. Although it is impossible …

Given the highly increased incidence of human diseases, a better understanding of the
related mechanisms regarding endogenous metabolism is urgently needed. Mass …

Herbal medicine (HM) has made a major contribution to the drug discovery process with
regard to identifying products compounds. Currently, more attention has been focused on …

Abstract Evaluation of the efficacy of traditional Chinese medicines (TCMs) is an important
prerequisite for discovering effective substances, lead compounds, and quality markers (Q …

Traditional natural product discovery affords no information about compound structure or
pharmacological activities until late in the discovery process and leads to low probabilities of …

Nutrient synergy refers to the concept that the combined effects of two or more nutrients
working together have a greater physiological impact on the body than when each nutrient is …