Therapeutic potential of quercetin: new insights and perspectives for human health
Quercetin (Que) and its derivatives are naturally occurring phytochemicals with promising
bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti …
bioactive effects. The antidiabetic, anti-inflammatory, antioxidant, antimicrobial, anti …
[HTML][HTML] Gut microbiota and dysbiosis in Alzheimer's disease: implications for pathogenesis and treatment
S Liu, J Gao, M Zhu, K Liu, HL Zhang - Molecular neurobiology, 2020 - Springer
Understanding how gut flora influences gut-brain communications has been the subject of
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
significant research over the past decade. The broadening of the term “microbiota-gut-brain …
Review on Alzheimer's disease: inhibition of amyloid beta and tau tangle formation
It is reported that approximately 40 million people are suffering from dementia, globally.
Dementia is a group of symptoms that affect neurons and cause some mental disorders …
Dementia is a group of symptoms that affect neurons and cause some mental disorders …
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease
Protein aggregation is the hallmark of neurodegeneration, but the molecular mechanisms
underlying late-onset Alzheimer's disease (AD) are unclear. Here we integrated …
underlying late-onset Alzheimer's disease (AD) are unclear. Here we integrated …
Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs
Abstract According to the Alzheimer Association Report (2017), Alzheimer's disease (AD) is
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
the 6th primary cause of death in the USA, which affects nearly 5.5 million people. In the …
[HTML][HTML] Reduction of Abeta amyloid pathology in APPPS1 transgenic mice in the absence of gut microbiota
T Harach, N Marungruang, N Duthilleul, V Cheatham… - Scientific reports, 2017 - nature.com
Alzheimer's disease is the most common form of dementia in the western world, however
there is no cure available for this devastating neurodegenerative disorder. Despite clinical …
there is no cure available for this devastating neurodegenerative disorder. Despite clinical …
Role of tau protein in Alzheimer's disease: The prime pathological player
Alzheimer's disease (AD) is a prevalently found tauopathy characterized by memory loss
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …
Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson's disease and Alzheimer's disease
T Jiang, Q Sun, S Chen - Progress in neurobiology, 2016 - Elsevier
Oxidative stress reflects an imbalance between the overproduction and incorporation of free
radicals and the dynamic ability of a biosystem to detoxify reactive intermediates. Free …
radicals and the dynamic ability of a biosystem to detoxify reactive intermediates. Free …
A review on Alzheimer's disease pathophysiology and its management: an update
A Kumar, A Singh - Pharmacological reports, 2015 - Elsevier
Alzheimer's disease acknowledged as progressive multifarious neurodegenerative disorder,
is the leading cause of dementia in late adult life. Pathologically it is characterized by …
is the leading cause of dementia in late adult life. Pathologically it is characterized by …
Amyloid-beta and phosphorylated tau accumulations cause abnormalities at synapses of Alzheimer's disease neurons
R Rajmohan, PH Reddy - Journal of Alzheimer's Disease, 2017 - content.iospress.com
Amyloid-beta (Aß) and hyperphosphorylated tau are hallmark lesions of Alzheimer's disease
(AD). However, the loss of synapses and dysfunctions of neurotransmission are more …
(AD). However, the loss of synapses and dysfunctions of neurotransmission are more …