A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …

A sustainable management of environment and agriculture is crucial to protect soil, water,
and air during intensified agriculture practices as well as huge industrial and transportation …

The gut microbiota (GM) is defined as the community of microorganisms (bacteria, archaea,
fungi, viruses) colonizing the gastrointestinal tract. GM regulates various metabolic pathways …

Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is
reported to modulate the development and neurogenesis of the enteric nervous system, gut …

Diseases of the central nervous system (CNS) remain a significant health, social and
economic problem around the globe. The development of therapeutic strategies for CNS …

The 'microbiota-gut-brain axis' plays a fundamental role in maintaining host homeostasis,
and different immune, hormonal, and neuronal signals participate to this interkingdom …

Environmental deterioration, global climate change, and consequent increases in pollution-
related health problems among populations have been attributed to growing consumption of …

The plasma kynurenine to tryptophan ([Kyn]/[Trp]) ratio is frequently used to express or
reflect the activity of the extrahepatic Trp-degrading enzyme indoleamine 2, 3-dioxygenase …

Recent data suggest gut microbiota dysbiosis as a contributing factor in neurodegenerative
diseases, such as Parkinson's Disease (PD) and Alzheimer's Disease (AD), and these …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common
neurodegenerative diseases (NDs), presenting a broad range of symptoms from motor …