The orexin/hypocretin neuropeptide family has emerged as a focal point of neuroscientific
research following the discovery that this family plays a crucial role in a variety of …

The hypothalamic neuropeptides orexin A and B (hypocretin 1 and 2) are important
homeostatic mediators of central control of energy metabolism and maintenance of …

Orexin is a neurotransmitter produced by a small group of hypothalamic neurons. Besides its
well-known role in the regulation of the sleep-wake cycle, the orexin system was shown to …

Typical body weight changes are known to occur in Parkinson's disease (PD). Weight loss
has been reported in early stages as well as in advanced disease and malnutrition may …

Orexins [orexin-A (OXA) and orexin-B (OXB)] are two isoforms of neuropeptides produced by
the hypothalamus. The main biological actions of orexins, focused on the central nervous …

Orexin A is produced in neurons of the lateral, perifornical and dorsomedial regions of the
lateral hypothalamic area, which then project widely throughout the central nervous system …

Orexin-A, a neuropeptide secreted by hypothalamic neurons, may be neuroprotective in
many neurological conditions such as cerebral ischaemia. One mechanism postulated to be …

Because binge eating and emotional eating vary through the menstrual cycle in human
females, we investigated cyclic changes in binge‐like eating in female rats and their control …

Interdisciplinary studies in the research fields of endocrinology and immunology show that
obesity-associated overnutrition leads to neuroinflammatory molecular changes, in …

Excess dietary saturated fatty acids such as palmitic acid (PA) induce peripheral and
hypothalamic inflammation. Hypothalamic inflammation, mediated in part by microglial …