Vascular calcification: mechanisms and clinical ramifications

M Abedin, Y Tintut, LL Demer - Arteriosclerosis, thrombosis, and …, 2004 - Am Heart Assoc
Vascular calcification, long thought to result from passive degeneration, involves a complex,
regulated process of biomineralization resembling osteogenesis. Evidence indicates that …

Atherothrombosis and high-risk plaque: part I: evolving concepts

V Fuster, PR Moreno, ZA Fayad, R Corti… - Journal of the American …, 2005 - jacc.org
Atherothrombosis is a complex disease in which cholesterol deposition, inflammation, and
thrombus formation play a major role. Rupture of high-risk, vulnerable plaques is …

Coronary plaque classification with intravascular ultrasound radiofrequency data analysis

A Nair, BD Kuban, EM Tuzcu, P Schoenhagen… - Circulation, 2002 - Am Heart Assoc
Background—Atherosclerotic plaque stability is related to histological composition.
However, current diagnostic tools do not allow adequate in vivo identification and …

Assessment of clinically silent atherosclerotic disease and established and novel risk factors for predicting myocardial infarction and cardiac death in healthy middle …

A Schmermund, S Möhlenkamp, A Stang… - American heart …, 2002 - Elsevier
Background In view of consistently high cardiovascular morbidity and mortality rates,
international efforts are aimed at developing tools for more precise risk prediction to allow …

Value of progression of coronary artery calcification for risk prediction of coronary and cardiovascular events: result of the HNR study (Heinz Nixdorf Recall)

N Lehmann, R Erbel, AA Mahabadi, M Rauwolf… - Circulation, 2018 - Am Heart Assoc
Background: Computed tomography (CT) allows estimation of coronary artery calcium
(CAC) progression. We evaluated several progression algorithms in our unselected …

Terminology for high-risk and vulnerable coronary artery plaques

JA Schaar, JE Muller, E Falk, R Virmani… - European heart …, 2004 - academic.oup.com
A group of investigators met for two days in Santorini, Greece, to discuss progress in the field
of identification and treatment of high risk/vulnerable atherosclerotic plaques and patients …

Running: the risk of coronary events: prevalence and prognostic relevance of coronary atherosclerosis in marathon runners

S Möhlenkamp, N Lehmann, F Breuckmann… - European heart …, 2008 - academic.oup.com
Aims To quantify the prevalence of coronary artery calcification (CAC) in relation to
cardiovascular risk factors in marathon runners, and to study its role for myocardial damage …

18F-FDG PET/CT identifies patients at risk for future vascular events in an otherwise asymptomatic cohort with neoplastic disease

A Rominger, T Saam, S Wolpers… - Journal of Nuclear …, 2009 - Soc Nuclear Med
Our objective was to evaluate the association of arterial 18F-FDG uptake and calcifications
in large arteries as detected by 18F-FDG PET/CT with the subsequent occurrence of …

Cardiac computed tomography: indications, applications, limitations, and training requirements: report of a Writing Group deployed by the Working Group Nuclear …

S Schroeder, S Achenbach, F Bengel… - European heart …, 2008 - academic.oup.com
As a consequence of improved technology, there is growing clinical interest in the use of
multi-detector row computed tomography (MDCT) for non-invasive coronary angiography …

Role of inflammation in atherosclerosis

LG Spagnoli, E Bonanno, G Sangiorgi… - Journal of nuclear …, 2007 - Soc Nuclear Med
Inflammation plays a major role in all phases of atherosclerosis. Stable plaques are
characterized by a chronic inflammatory infiltrate, whereas vulnerable and ruptured plaques …