Idiopathic pulmonary fibrosis (IPF): an overview

SL Barratt, A Creamer, C Hayton… - Journal of clinical …, 2018 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic,
progressive scarring of the lungs and the pathological hallmark of usual interstitial …

Nintedanib: a review in fibrotic interstitial lung diseases

YN Lamb - Drugs, 2021 - Springer
Progressive fibrosing interstitial lung diseases (ILDs) involve similar pathophysiological
processes, indicating the potential for common approaches to treatment. Nintedanib …

Targeting histone deacetylases in idiopathic pulmonary fibrosis: a future therapeutic option

M Korfei, P Mahavadi, A Guenther - Cells, 2022 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited
therapeutic options, and there is a huge unmet need for new therapies. A growing body of …

Redox imbalance in idiopathic pulmonary fibrosis: a role for oxidant cross-talk between NADPH oxidase enzymes and mitochondria

C Veith, AW Boots, M Idris, FJ van Schooten… - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Idiopathic pulmonary fibrosis (IPF) is a progressive age-related lung disease
with a median survival of only 3 years after diagnosis. The pathogenic mechanisms behind …

Inhibitors of the autotaxin-lysophosphatidic acid axis and their potential in the treatment of interstitial lung disease: current perspectives

S Zulfikar, S Mulholland, H Adamali… - Clinical pharmacology …, 2020 - Taylor & Francis
Idiopathic pulmonary fibrosis is a progressive fibrosing interstitial lung disease for which
there is no known cure. Currently available therapeutic options have been shown at best to …

Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic …

M Korfei, D Stelmaszek, BA MacKenzie, S Skwarna… - PloS one, 2018 - journals.plos.org
Background Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease with a poor
prognosis. Pirfenidone is the first antifibrotic agent to be approved for IPF-treatment as it is …

Alternative oral agents in prophylaxis and therapy of uterine fibroids—an up-to-date review

M Ciebiera, K Łukaszuk, B Męczekalski… - International Journal of …, 2017 - mdpi.com
Uterine fibroids (UFs) are the most common tumors of the female genital tract. The effect of
UFs on the quality of life and the overall cost of treatment are significant issues worldwide …

Use of Chou's 5-Steps Rule to Reveal Active Compound and Mechanism of Shuangshen Pingfei San on Idiopathic Pulmonary Fibrosis

Y Chen, X Fan - Current Molecular Medicine, 2020 - ingentaconnect.com
Background: Shuangshen Pingfei San (SPS) is the derivative from the classic formula
Renshen Pingfei San in treating idiopathic pulmonary fibrosis (IPF). Methods: In this study …

Financial toxicity: a common but rarely discussed treatment side effect

C McDermott - Annals of the American Thoracic Society, 2017 - atsjournals.org
The most memorable part of my San Francisco trip was stopping at the crest of each hill,
small or large, to “admire the view.” In truth, my legs were leaden and I was gasping for air …

A Review of the Current Landscape of Anti-Fibrotic Medicines

AR Lapthorn, SL Harding, KM Feltham… - 2024 - aru.figshare.com
Fibrosis is defined as the excessive accumulation and disorganized deposition of
extracellular matrix components, affecting any organ in the human body. Fibrotic diseases of …