Traditional drug discovery mainly focuses on direct regulation of protein activity. The
development and application of protein activity modulators, particularly inhibitors, has been …

Background The world is in the midst of the COVID-19 pandemic. In this comprehensive
review, we discuss the potential protective effects of (−)-epigallocatechin-3-gallate (EGCG) …

(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Heat shock proteins (HSPs) are a large group of chaperones found in most eukaryotes and
bacteria. They are responsible for the correct protein folding, protection of the cell against …

COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which infected> 200 million people resulting in> 4 million deaths. However, temporal …

Hepatitis B virus (HBV) infection is a major driver of hepatocarcinogenesis. Ferroptosis is a
type of iron-mediated cell death that can suppress liver transformation. Previous studies …

Heat shock proteins (HSPs) are a kind of proteins which mostly found in bacterial, plant and
animal cells, in which they are involved in the monitoring and regulation of cellular life …

The main purpose of this article is to present the latest research related to selected
biological properties of carvacrol, such as antimicrobial, anti-inflammatory, and antioxidant …

Understanding the factors that shape viral evolution is critical for developing effective
antiviral strategies, accurately predicting viral evolution, and preventing pandemics. One …

Studying viral–host protein–protein interactions can facilitate the discovery of therapies for
viral infection. We use high-throughput yeast two-hybrid experiments and mass spectrometry …