Micro RNA regulation of T‐cell differentiation and function
LT Jeker, JA Bluestone - Immunological reviews, 2013 - Wiley Online Library
Micro RNA s (mi RNA s) are emerging as key controllers of T‐cell differentiation and
function. Their expression is dynamically regulated by extracellular signals such as …
function. Their expression is dynamically regulated by extracellular signals such as …
Specificity factors in cytoplasmic polyadenylation
A Charlesworth, HA Meijer… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
Poly (A) tail elongation after export of an messenger RNA (mRNA) to the cytoplasm is called
cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has …
cytoplasmic polyadenylation. It was first discovered in oocytes and embryos, where it has …
A global survey of full-length transcriptome of Ginkgo biloba reveals transcript variants involved in flavonoid biosynthesis
J Ye, S Cheng, X Zhou, Z Chen, SU Kim, J Tan… - Industrial Crops and …, 2019 - Elsevier
Ginkgo biloba, which contains flavonoids as bioactive components, is widely used in
traditional Chinese medicine. Increasing the flavonoid production of medicinal plants …
traditional Chinese medicine. Increasing the flavonoid production of medicinal plants …
[HTML][HTML] Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition
RNA-binding proteins (RBPs) and long non-coding RNAs (lncRNAs) are key regulators of
gene expression, but their joint functions in coordinating cell fate decisions are poorly …
gene expression, but their joint functions in coordinating cell fate decisions are poorly …
Position-specific binding of FUS to nascent RNA regulates mRNA length
A Masuda, J Takeda, T Okuno, T Okamoto… - Genes & …, 2015 - genesdev.cshlp.org
More than half of all human genes produce prematurely terminated polyadenylated short
mRNAs. However, the underlying mechanisms remain largely elusive. CLIP-seq (cross …
mRNAs. However, the underlying mechanisms remain largely elusive. CLIP-seq (cross …
E2F mediates enhanced alternative polyadenylation in proliferation
R Elkon, J Drost, G van Haaften, M Jenal, M Schrier… - Genome biology, 2012 - Springer
Background The majority of mammalian genes contain multiple poly (A) sites in their
3'UTRs. Alternative cleavage and polyadenylation are emerging as an important layer of …
3'UTRs. Alternative cleavage and polyadenylation are emerging as an important layer of …
APAtrap: identification and quantification of alternative polyadenylation sites from RNA-seq data
Motivation Alternative polyadenylation (APA) has been increasingly recognized as a crucial
mechanism that contributes to transcriptome diversity and gene expression regulation. As …
mechanism that contributes to transcriptome diversity and gene expression regulation. As …
Benchmarking sequencing methods and tools that facilitate the study of alternative polyadenylation
Background Alternative cleavage and polyadenylation (APA), an RNA processing event,
occurs in over 70% of human protein-coding genes. APA results in mRNA transcripts with …
occurs in over 70% of human protein-coding genes. APA results in mRNA transcripts with …
Alternative polyadenylation alters protein dosage by switching between intronic and 3′ UTR sites
Alternative polyadenylation (APA) creates distinct transcripts from the same gene by
cleaving the pre-mRNA at poly (A) sites that can lie within the 3′ untranslated region (3 …
cleaving the pre-mRNA at poly (A) sites that can lie within the 3′ untranslated region (3 …
On the function and relevance of alternative 3′‐UTRs in gene expression regulation
I Pereira‐Castro, A Moreira - Wiley Interdisciplinary Reviews …, 2021 - Wiley Online Library
Messanger RNA (mRNA) isoforms with alternative 3′‐untranslated regions (3′‐UTRs) are
produced by alternative polyadenylation (APA), which occurs during transcription in most …
produced by alternative polyadenylation (APA), which occurs during transcription in most …