Exploring the HSA/DNA/lung cancer cells binding behavior of p-Synephrine, a naturally occurring phenyl ethanol amine with anti-adipogenic activity: multi …

R Taheri, N Hamzkanlu, Y Rezvani… - Journal of Molecular …, 2022 - Elsevier
As a phenolic amine, p-Synephrine (SN) is known to exhibit lipolytic properties as well as
enhancing energy expenditure, which can be an excellent alternative to ephedra as a …

Investigation on the binding behavior of human α1-acid glycoprotein with Janus Kinase inhibitor baricitinib: Multi-spectroscopic and molecular simulation …

SL Jiang, ZY Hu, WJ Wang, L Hu, L Li, SB Kou… - International Journal of …, 2023 - Elsevier
Abstract Baricitinib is a Janus Kinase (JAK) inhibitor that is primarily used to treat moderately
to severely active rheumatoid arthritis in adults and has recently been reported for the …

[HTML][HTML] A comprehensive investigation of interactions between antipsychotic drug quetiapine and human serum albumin using multi-spectroscopic, biochemical, and …

S Zargar, TA Wani, NA Alsaif, AIA Khayyat - Molecules, 2022 - mdpi.com
Quetiapine (QTP) is a short-acting atypical antipsychotic drug that treats schizophrenia or
manic episodes of bipolar disorder. Human serum albumin (HSA) is an essential transport …

[HTML][HTML] Influence of rutin, sinapic acid, and naringenin on binding of tyrosine kinase inhibitor erlotinib to bovine serum albumin using analytical techniques along with …

TA Wani, AH Bakheit, S Zargar, AIA Khayyat… - Applied Sciences, 2022 - mdpi.com
Flavonoid-containing food supplements are widely used as antioxidants, and the continuous
use of these supplements with other drugs can lead to clinically significant interactions …

A double-edged sword: focusing on potential drug-to-drug interactions of quercetin

K Ding, H Jia, W Jiang, Y Qin, Y Wang, M Lei - Revista Brasileira de …, 2023 - Springer
Herbal and herbal dietary supplements have a massive share of the global market, and their
use continues to grow worldwide. There is a general perception that herbal and herbal …

Imperative persistent interaction analysis of anticancer noscapine-ionic liquid with calf thymus DNA

H Sehrawat, N Kumar, S Panchal, L Kumar… - International Journal of …, 2022 - Elsevier
In this study, we have shown the interaction between opium poppy alkaloid noscapine-
based ionic liquid [Pip-Nos] OTf and ct-DNA using UV–visible absorption spectroscopy …

Effect of glycation of bovine serum albumin on the interaction with xanthine oxidase inhibitor allopurinol: Spectroscopic studies and molecular modeling

N Rahman, N Khalil - Journal of Molecular Liquids, 2022 - Elsevier
Serum albumin is glycated in diabetic or hyperglycemic conditions. For in vitro experiments
bovine serum albumin (BSA) is employed as a transport protein. So, in this work, we aim to …

An insight into the interaction between Indisulam and human serum albumin: Spectroscopic method, computer simulation and in vitro cytotoxicity assay

B Zhou, H Zhou, L Xu, R Cai, C Chen, B Chi, X Tuo - Bioorganic Chemistry, 2022 - Elsevier
Indisulam (IDM) is a sulfanilamide anticancer agent and has been identified as a molecular
glue recently. It shows potential for novel therapies development and brings more hope for …

[HTML][HTML] Evaluation of the Possible Pathways Involved in the Protective Effects of Quercetin, Naringenin, and Rutin at the Gene, Protein and miRNA Levels Using In …

S Zargar, N Altwaijry, TA Wani, HM Alkahtani - Molecules, 2023 - mdpi.com
Flavonoids are secondary metabolites that are non-essential for plant growth or survival,
and they also provide numerous health benefits to humans. They are antioxidants that shield …

Binding of dicoumarol analog with DNA and its antioxidant studies: A biophysical insight by in-vitro and in-silico approaches

K Lavanya, PV Babu, ATS Bodapati, RS Reddy… - International Journal of …, 2023 - Elsevier
DNA is the major target for a number of pharmaceutical drugs. The interaction of drug
molecules with DNA plays a major role in pharmacokinetics and pharmacodynamics. Bis …