A 7-month inhalation toxicology study in C57BL/6 mice demonstrates reduced pulmonary inflammation and emphysematous changes following smoking cessation or …

A Kumar, U Kogel, M Talikka, C Merg… - Toxicology …, 2021 - journals.sagepub.com
Cigarette smoking causes serious diseases, including lung cancer, atherosclerotic coronary
artery disease, peripheral vascular disease, chronic bronchitis, and emphysema. While …

Acute vaping in a golden Syrian hamster causes inflammatory response transcriptomic changes

DM Hinds, HJ Nick, TM Vallin… - … of Physiology-Lung …, 2022 - journals.physiology.org
E-cigarette vaping is a major aspect of nicotine consumption, especially for children and
young adults. Although it is branded as a safer alternative to cigarette smoking, murine and …

GC/HRMS Analysis of E-Liquids Complements In Vivo Modeling Methods and can Help to Predict Toxicity

I Walker-Franklin, RU Onyenwoke, TC Leung… - ACS …, 2024 - ACS Publications
Tobacco smoking is a major risk factor for disease development, with the user inhaling
various chemicals known to be toxic. However, many of these chemicals are absent before …

[HTML][HTML] Tobacco-derived and tobacco-free nicotine cause differential inflammatory cell influx and MMP-9 in mouse lung

T Lamb, G Kaur, I Rahman - Respiratory Research, 2024 - Springer
Background Electronic nicotine delivery systems (ENDS) or electronic cigarettes (e-
cigarettes) aerosolize an e-liquid composed of propylene glycol (PG) and vegetable glycerin …

Electronic cigarettes and their impact on allergic respiratory diseases: a work group report of the AAAAI Environmental Exposures and Respiratory Health Committee

ML Hernandez, AJ Burbank, NE Alexis… - The Journal of Allergy …, 2021 - Elsevier
The explosive rise in popularity of electronic cigarette (e-cig) devices over the past decade
has led to controversies over the role of these devices in smoking cessation and harm …

[HTML][HTML] E-cigarette vapor renders neutrophils dysfunctional due to filamentous actin accumulation

AE Jasper, AA Faniyi, LC Davis, FS Grudzinska… - Journal of Allergy and …, 2024 - Elsevier
Background Electronic cigarette (e-cigarette) use continues to rise despite concerns of long-
term effects, especially the risk of developing lung diseases such as chronic obstructive …

Prolonged, physiologically relevant nicotine concentrations in the airways of smokers

CR Esther Jr, WK O'Neal, NE Alexis… - … of Physiology-Lung …, 2023 - journals.physiology.org
Nicotine from cigarette smoke is a biologically active molecule that has pleiotropic effects in
the airway, which could play a role in smoking-induced lung disease. However, whether …

Impact of inhaled pollutants on response to viral infection in controlled exposures

ME Rebuli, SA Brocke, I Jaspers - Journal of Allergy and Clinical …, 2021 - Elsevier
Air pollutants are a major source of increased risk of disease, hospitalization, morbidity, and
mortality worldwide. The respiratory tract is a primary target of potential concurrent exposure …

The paradox of the safer cigarette: understanding the pulmonary effects of electronic cigarettes

K Allbright, J Villandre, LEC Alexander… - European …, 2024 - Eur Respiratory Soc
Electronic cigarette (e-cigarette) use continues to rise globally. E-cigarettes have been
presented as safer alternatives to combustion cigarettes that can mitigate the harm …

The impact of smoking on bronchiectasis and its comorbidities

D de la Rosa-Carrillo, JI de Granda-Orive… - Expert Review of …, 2024 - Taylor & Francis
Introduction Bronchiectasis, characterized by irreversible bronchial dilatation, is a growing
global health concern with significant morbidity. This review delves into the intricate …