Bone is an extremely dynamic tissue, undergoing continuous remodeling for its whole
lifetime, but its regeneration or augmentation due to bone loss or defects are not always …

Osteoarthritis (OA) is a prevalent, disabling disorder of the joints that affects a large
population worldwide and for which there is no definitive cure. This review provides critical …

Mitochondrial components have been abundantly detected in bone matrix, implying that they
are somehow transported extracellularly to regulate osteogenesis. Here, we demonstrate …

Background Differentiation of mesenchymal stem cells to osteoblasts is widely performed in
research laboratories. Classical tests to prove this differentiation employ procedures such as …

The pathogenesis of declining bone mineral density, a universal feature of ageing, is not
fully understood. Somatic mitochondrial DNA (mtDNA) mutations accumulate with age in …

This study represents the unique analysis of the electrospun scaffolds with the controlled
and stable surface potential without any additional biochemical modifications for bone tissue …

Some anti-diabetic therapies can have adverse effects on bone health and increase fracture
risk. In this study, we tested the skeletal effects of chronic administration of two Glucagon-like …

Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as
hydroxyapatite, in the medial layer of the arteries. AMC shares some similarities to skeletal …

Background Rapid, non-genomic estrogen receptor (ER) signaling plays an integral role in
mediating the tissue selective properties of ER modulators. Icariin, a bone bioactive …

Custom-made biocompatible titanium alloy mesh can be designed to facilitate the
regeneration of alveolar bone defects by supporting a protected space and inhibiting …